39 results
This study has been transitioned to CTIS with ID 2024-520305-39-00 check the CTIS register for the current data. Primary objective: to evaluate the efficacy of LSD 25µg every 3 days for 3 weeks in cCH. Additional objectives:- To evaluate the safety…
The objective of the study is to assess the effect of music on postictal agitation when played peri-interventionally for patients undergoing electroconvulsive therapy for severe depression.
The ultimate goal is to investigate whether aVNS can enhance cortical plasticity and improve functional outcomes during intensive rehabilitation programs in children with cerebral palsy. First, we aim to establish the extent of cortical plasticity…
Primary objectives:• To characterize the central inflammatory response to IV LPS by measuring biomarkers in CSF• To characterize the systemic inflammatory response to IV LPS by measuring biomarkers in blood • Characterize CSF/Blood ratios for each…
To investigate the effect of nutritional prehabilitation on adverse events in patients with locoregionally advanced head and neck cancer, with low to medium risk of malnutrition and with radiological sarcopenia. To evaluate its effect on patient-…
The main objective is to replicate the results of the recent successful efficacy study on precuneus rTMS in AD by Koch et al. (2022). Secondary objectives include investigating what functional brain activity/network changes underlie the effects of…
To assess the impact of a nutritional formulation containing caprylic acid and omega 3 fatty acids on skeletal muscle function recovery from damaging exercise.
The objective of this project is to test the clinical and cost effectiveness of utilizing the assessment of transdiagnostic dynamics of symptoms to provide a personalized e-health treatment intervention as an automated tool during the waiting list…
The primary objective is to examine the effect of twelve weeks supplementing daily one AstaPure® Oleoresin capsule on trans epidermal water loss (TEWL) in postmenopausal women. The secondary objectives are to investigate the effects on other skin,…
The primary objective of the study is to investigate the medium to long term effects of replacing the conventional CXR exam with an ultra-low-dose CT in terms of patient health.Secondary outcomes are measures are • Quantity and type of follow-up…
To acquire metabolic health data from three dietary challenge meals for the development of an algorithm for personalised dietary advice, and subsequently test the effectiveness of this personalised dietary advice compared to a general healthy diet…
Our study aims to identify unique Metabotypes among individuals with overweight at risk of T2DM and assess their response to a 1-year precision dietary macronutrient modulation. The objective is to provide proof-of-concept that this approach…
The primary objective is feasibility of a prospective randomized trial, to investigate whether a more restrictive RBC transfusion strategy of 5.0 g/dL (3.1 mmol/L) is non-inferior compared to the current transfusion threshold of 7.0 g/dL (4.3mmol/L…
A pilot study on digital coaching in rUTI at the Urology Department of Isala tested an app-based treatment additional to standard care.[8] The app provides information on rUTI aetiology, lifestyle recommendations, treatments, and the value of…
To evaluate the contribution in terms of information provision and patients* perspectives of ICU-VR to prepare lung transplant patients for their future ICU admission
The primary objective is to evaluate the effectiveness of dietary nitrate in reducing muscle atrophy induced by bedrest. Secondary objectives include assessing its impact on insulin resistance, muscle strength, and cardiovascular function.…
To demonstrate the clinical efficacy and safety profile of canaloplasty utilizing the iTrackTM Advance canaloplasty device performed via an ab-interno surgical technique achieves:1. Enhanced IOP reduction at 12 months due to the techniques ability…
The main objective of this study is to assess the feasibility, safety and (cost-)effectiveness of the HOME-ART intervention in comparison to regular hospital admission in patients with CA-ARTI.
To evaluate the effect of combined PVE/HVE compared to PVE alone on resectability and overall survival in patients with primary liver cancers.
The aim of this RCT is to examine the differences in functional, clinical, and radiological out-comes, between LCP fixation alone and femoral allograft augmentation in addition to LCP. Ultimately, the purpose is to optimize treatment strategies and…