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A Double-Blind, Randomized, Placebo-controlled Study of Two Different Schedules of Palifermin (Pre-and Post Chemotherapy and Pre-Chemotherapy only) for Reduction in Severity of Oral Mucositis in Subjects with Multiple Myeloma (MM) Receiving High Dose Melphalan followed by Autologous Peripheral Blood Stem Cell Transplantation (PBSCT)

The primary objective is to compare the efficacy of palifermin relative to placebo when given either pre-and post-high dose chemotherapy or pre-high dose chemotherapy only with regard to the severity of oral mucositis.

Diagnosis of Laryngopharyngeal Reflux (LPR) in patients with Hoarseness and Globus: is aerosolized oropharyngeal pH monitoring adequate?

Primary objective: to objectively diagnose LPR in patients with hoarseness and/or globus complaints, and a Reflux Symptom Index (RSI) > 13. Secondary objective: To asses the accuracy of the Restech Dx-pH probeTM compared to the dual 24h pH…

Divergent Low Level Laser Therapy as novel treatment for oral mucositis in pediatric cancer patients

Primary Objective: - To assess the effect of divergent LLLT on the number of days of mucositis > grade 1Secondary Objective(s): - To assess the effect of divergent LLLT on the severity of mucositis - To assess the effect of divergent LLLT on…