1026 results
Focusing on disease-modifying rather than etiologic mechanisms may accelerate the development of novel therapies and complement current research initiatives on causative mechanisms and curative therapies.
Education on guidelines, combined with quality targets within the accreditation procedure improves quality of antibiotic prescribing
Different prevention strategies are used internationally to prevent Early-onset Group B haemolytic streptococcus infection (EOGBS). However, none of the preventive EOGBS strategies in place at present result in the complete prevention of EOGBS,…
We postulate that exhaled molecular profiling obtained from ‘breathprints’ by electronic nose: 1. Is associated with the level of asthma control and; 2. Is associated with an inflammatory profile in induced sputum and blood in steroiddependent…
Muscle hypoxia, either chronic or intermittent (exercise-induced), is responsible for the altered muscle oxidative phenotype in chronic obstructive pulmonary disease and chronic heart failure through modulation of the regulatory molecules PGC-1/…
Antireflux surgery is one of the most common major operations performed in pediatric patients. Most studies on the outcome of antireflux surgery in children are limited to retrospective data, case reports or are based solely on symptoms. A…
Submucous fibroids are known to be related to heavy menstrual bleeding (HMB), dysmenorrhea and fertility problems. Transcervical resection of fibroids (TCRM) is a widely implemented treatment for submucous fibroids, to be precise FIGO PALM-COEIN…
1. To determine the reproducibility and sensitivity of the Energy Cost of Walking test (ECWT) in boys with Duchenne muscular dystrophy, in comparison with the reproducibility and sensitivity of the 6-Minute Walk Test (6MWT); 2. To evaluate the 1-…
The primary objective of this study is to determine whether thrombectomy combined with ischemic postconditioning after PCI leads to a smaller myocardial infarction compared to standard therapy.
In primary prostate cancer patients, the exisstence of lymph node metastases is associated with developmment of distant metastases and negatively associated with cancer-specific survival. The performance of an extended lymph node dissection (ePLND…
The purpose of this research is to acquire a better understanding of the pain experience and the recovery of children between 1.5 and 5 years old who underwent a tonsillectomy/adenotonsillectomy. Primary research question: What is the influence of…
Part A: In clinical practice the use of simplified quantitative methods and procedures can be fully validated against complex quantitative kinetic measures. Part B: Test-retest repetability of different SUV measures, metabolic and anatomic volume…
The Victoria modules are thought to have a positive effect on acknowlegdement for adversities and risk awareness. This can be used to take acceptable risks in rehabilitation process. This will then lead to more societal participation and less…
we hypothesize that there is a link between gut microbiota composition and development of venous thrombosis.
The national quality improvement program palliative care will improve quality of palliative care on a national level and the separate trajectories implementing ‘good practices’ will improve quality of palliative care on the regional and…
Muscular counterpulsation (MCP) is a new treatment option which seems to improve hemodynamics but might also have positive effects on muscular and vascular function. Additionally, it is non-invasive and does not seem to have relevant side effects.…
An intensive rectal wash-out program for constipated girls with NNBSD is as effective in curing recurrent urinary tract infections as cognitive bladder training in standard outpatient treatment.
Oral pazopanib once daily is safe and effective in advanced endometrial cancer for which no other therapies are available.
Previous randomised trials have shown the efficacy of etanercept in RA patients. In this study we will evaluate the respons of etanercept in anti-TNF naive patients compared to patients who have failed other anti-TNF. We will look for clinical…
Donor-specific antibodies form a significant barrier in transplantation of highly pre-sensitized dialysis patients. Increased waiting time is associated with increased morbidity and mortality among these patients. Thus, there is a need to further…