245 results
The main objective of this study is to investigate the effect of cerebellar tDCS on impulsivity in healthy adults.
To assess the safety, tolerability, biomarker and cognitive efficacy of investigational products in subjects who are known to have an Alzheimer*s disease-causing mutation by determining if treatment with the study drug slows the rate of progression…
To investigate whether perturbation of the left middle temporal gyrus results in immediate adaptation in the right hemisphere, indexed by a shift of alpha-beta oscillatory effects from the left to the right hemisphere.
PRP injections are efficacious for symptom reduction and functional improvement compared to placebo injections in the treatment of ankle (talocrural) OA.
• To evaluate the safety and tolerability of three oral dose levels of LTI-291 following 28 days of LTI-291 treatment in patients with Parkinson’s Disease with GBA-PD. • To characterize the plasma and CSF pharmacokinetics (PK) of LTI-291 following…
In the proposed study we will investigate the effect
Recurrent respiratory tract infections (RTIs) affect 15-20% of children aged 0-5 years and cause high disease burden, frequent doctor visits and are one of the main reasons for hospital admission in childhood. Despite the common use of co-…
Music interventions will reduce anxiety and pain in patients undergoing a nuss bar procedure due to pectus excavatum
The primary hypothesis is that preconscious attention bias modification (ABM) training towards and away from pictorial itch stimuli results in altered preconscious attention for pictorial itch stimuli. Secondarily, it will be explored whether…
Effectiveness of Moving Stories, a game-based school program aimed at depression literacy and stigma
Our first hypothesis is that adolescents who’ve participated in the Moving Stories program will have better mental health literacy and fewer stigmas regarding depression than adolescents who have not participated, both at posttest and at three- and…
Ghrelin administration in comatose patients after cardiac arrest is safe, causes no serious adverse events relatable to ghrelin use and it improves functional recovery in these patients.
Crohn’s disease (CD) is a chronic inflammatory bowel disorder (IBD) with a major impact on quality of life. Mucosal healing is an important treatment outcome to prevent long term complications of the disease. Regulatory M2 type macrophages play a…
It is hypothesized that this personally tailored physical activity program (I’M FINE intervention) will be more effective in improving physical fitness and enhance daily activity in individuals with slowly progressive neuromuscular diseases (NMD)…
What is the influence of protective gear on the performance of basic life support (BLS) by KNRM lifeboat crewmembers during a manikin simulation training
Compared to placebo treatment with low dose amitriptyline or mirtazapine during 16 weeks will improve subjective insomnia in insomnia disorder patients in general practice.
Respiratory Syncytial Virus (RSV) is still the leading cause of hospitalization of children under 5 years of age. Currently, there is no effective treatment licensed for an ongoing RSV infection. Therefore, Intravacc develops a live-attenuated…
1. An early screening at 1y of corrected age will identify preterm children with an increased risk of developing visual processing dysfunctions 2. Early visual rehabilitation from 1y of corrected age will benefit the visual and neurocognitive…
We expect that treatment with azelastine/fluticasone propionate will decrease exercise tolerance limitation and will improve quality of life.
We hypothesize that probiotics with vitamin K2 producing properties can improve vitamin K status.
THypothesis: The integration of measurement outcomes in response to the PhenFlex challenge test will enlarge small, single differences by combining multiple but small effects on metabolism leading eventually to a measurable health difference before…