21 results
The primary objective is to determine whether subjects with CIDP are overtreated with maintenance IVIg treatment and to reduce overtreatment-associated subjects* burden and health care costs.
Primary Objectives: * To determine if NA patients have altered cerebral activity related to motor planning of their affected arm compared to healthy controls and compared to their non-affected arm.* To determine if specific rehabilitation focused on…
The aim of the research is to study the effectiveness of PRF treatment on radicular neuropathic pain. The effectiveness will be determined by eQST, VAS and RAND-36 values. To evaluate the effectiveness of the PRF treatment, there will be included a…
Primary objective:To assess the safety of repeat applications of QUTENZA administered over a period of 12 months in subjects with PDPN.Secondary objectives:To assess the efficacy of repeat applications of QUTENZA administered over a period of 12…
To evaluate the effect of surgical decompression of the nerves in the lower extremities in patients with painful diabetic neuropathy.
What is the long-term clinical benefit of best medical practice with and without adjunctive SCS Therapy in patients with chronic diabetic neuropathic pain?
To investigate if:-Kiovig is at least as effective as Gammagard. (equivalence)-Kiovig has a good side effect profile for CIDP patients.-Whether patients prefer Kiovig to Gammagard.
To what extent does the use of therapeutic footwear, which is prescribed and monitored using plantar pressure distribution assessment, result in a reduced plantar ulcer recurrence rate compared to the use of therapeutic footwear which is prescribed…
Primary objective is to study the number of patients gaining at least 50% pain reduction within 8 weeks following PRF as compared to following a neurectomy. Pain intensity will be measured using numeric pain rating score (NPRS, 0-10) and Verbal…
This study has been transitioned to CTIS with ID 2024-511008-17-00 check the CTIS register for the current data. To assess whether lacosamide is as efficient in the treatment of chemotherapy-induced neuropathic pain as duloxetine
To make an evidence-based recommendation on which method has the best efficacy (PROM), patient treatment experience (PREM) and safety profile (complications).
Prevention of diminished hand sensibility (and secondary: hand function) after trans radial access coronary angiography by shorter wrist compression time using Statseal hemostasis.
The main objective is to assess whether Bediol (containing THC and CBD) co-treatment will reduce opioid side effects in chronic pain patients. A secondary objective will be that Bediol is superior to oxycodone in the relief of chronic fibromyalgia…
The goal of this study is to examine the effectiveness of an online psychological intervention based on Acceptance and Commitment Therapy (ACT) in a Randomized Controlled Trial (RCT) and compared to a treatment-as-usual control condition (TAU). We…
Primary objective:To evaluate the efficacy of ION-682884, based on the change from Baseline in serum Transthyretin (TTR) concentration, modified Neuropathy Impairment Score +7 (mNIS+7), and Norfolk Quality of Life Questionnaire-Diabetic Neuropathy (…
The objective of this study is to assess the efficacy and cost-effectiveness of a treatment strategy starting with surgical intervention compared to a starting treatment with steroid injection.
The primary research question of the trial is to assess whether foot drop, caused by peroneal nerve entrapment in adult patients* recovers better within 9 months after decompressive surgery compared to prolonged standard conservative treatment. *…
Primary Objective: to show a reduction in eGFR decline in patients treated with LCP tacrolimus compared to IR tacrolimus. Secondary objectives will include investigating the potential decline in other known side effects of calcineurin inhibitors i.e…
The primary objective is to determine whether in patients with CIPN pain, treatment with Qutenza has the same effect as treatment with duloxetine
To evaluate the effect of peripheral nerve decompression surgery in patients with headache caused by entrapment neuropathy,comparing it to conventional treatment.