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Differences in inflammatory and hemostatic response in cardiac surgery patients operated with conventional Cardiopulmonary Bypass (CPB) versus Minimized Extracorporeal Circulation (MECC).

The primary objective of this study is to define differences in the inflammatory response, coagulation, and fibrinolysis in CABG patients with either MECC or conventional CPB.

Implementation of a concept for active primary prevention of type 2 diabetes in a primary care setting.

Objective is to study the implementation of a proven cocept for active primary prevention of type 2 diabetes in a Dutch primary care setting, in order to assess whether such a concept can be applied on a broader scale, and as such contribute to the…

Disease modifying activity of celecoxib on articular cartilage in osteoarthritis

To evaluate, in patients with end stage knee osteoarthritis, the in vivo disease (tissue structure) modifying activity of celecoxib, as a selective COX-2 inhibitor, in addition to its inflammation regulatory properties, compared to naproxen as a…

Evaluation of intubation conditions comparing three video-assisted laryngoscopes.

We compared three video-assisted laryngoscopes (RangerTM, Glidescope; Storz videolaryngoscopeTM Tuttlingen, Germany and McGrath scopeTM, Aircraft Medical, Edinburgh, UK) in 300 patients undergoing general anaesthesia and aimed to compare: intubation…

Effects of a mindfulness based stress reduction program on psychological, cognitive and physiological measures in PCI-patients.

The aim is to evaluate the effectivity of training in mindfulness with patient who underwent a PCI-procedure on different variables: (i) psychological wellbeing (mood, anxiety, depression and quality of life), (ii) clinical relevant physiological…