264 results
This proof-of-principle evaluation aims to investigate whether a home-based balance training using an exergame (HEROES), following a single session of perturbation-based training improves reactive step quality in people with chronic stroke.
The aim of the two separate studies is as follows: 1. To evaluate the effect of perioperative micronised lipofilling in patients with ORIF of P1 fractures on postoperative range of motion2. To evaluate the effect of perioperative micronised…
The primary objective of this study is to investigate the effectiveness of TE-ST in enhancing personality functioning as compared to long-term schema group therapy. Secondary objectives to the study are: to explore the effect on reducing general…
The primary objective is to compare post-transplant outcome after a 6 hour period of NMP immediately prior to transplantation following standard hypothermic machine perfusion (HMP), to outcome after standard HMP alone of 50+ deceased-donor kidneys.…
The aim of this study is to investigate whether the type of surgical approach to the cochlea; CO or eRW using the Nucleus 632 with the Slim Modiolar electrode affects the final residual hearing and secondarily, intracochlear trauma and electrode…
The aim of this study is to assess the clinical suitability of PEEK bonded retainers and to evaluate its successes and failures compared to the current clinical *golden standard* multibraided stainless steel bonded retainer wires.Null Hypothesis:…
This randomised double-blind placebo-controlled study will investigate the effects of a oligofructose vs a placebo on (change in) stool consistency in healthy children with hard stools. Other parameters to be investigated include (change in) stool…
This intervention study aims to investigate the effects of daily administration of a prebiotic fiber mixture in a Nutritionally Complete Oral Nutritional Supplement (ONS) for 8-9 weeks on intestinal microbiota composition and diversity in patients…
To study the efficacy of preoperative CBM in patients with increased anxiety levels undergoing knee- or spine surgery with expected postoperative moderate to severe pain.
This study has been transitioned to CTIS with ID 2024-517700-12-00 check the CTIS register for the current data. To improve disease-free survival in patients with high-risk rectal cancer by treating these patients with adjuvant chemotherapy in case…
The main objective of this trial is to investigate whether HAIP with concomitant systemic therapy prolongs overall survival in chemo-naive patients with initially unresectable synchronous colorectal liver metastases as compared with systemic therapy…
The aim is to address the following research question:Is there a higher incidence of postoperative (wound) infections when utilizing maximally hygienic measures instead of sterile measures in elective laparoscopic cholecystectomies?Secondary…
The objective of the diagnostic performance study is to determine the KRAS G12C status in tissues of NSCLC tumors collected from potential study subjects, in order to determine their biomarker eligibility for study BO45217. Currently, there is no…
To study the impact of tVNS on gut motor function, in particular with regards to its potential to induce phase III contractions in the upper GI tract, in healthy subjects.
The primary objective of this study is to investigate the efficacy of EMDR therapy in reducing pain interference in the life*s of children with SCD. Secondary objectives are to study the efficacy of EMDR in reducing PTSD symptoms, anxiety,…
In this study, we aim to compare two different techniques for the second ablation in patients who have previously undergone an unsuccessful ablation. The first technique is called "radiofrequency ablation," and the second technique is…
Objectives: To test the effectiveness and safety of TTFields, delivered using the NovoTTF-200T device, concomitant with pembrolizumab and platinum-based chemotherapy in subjects with metastatic non-small cell lung cancer (NSCLC)
In this research, we are comparing two distinct physiotherapy treatments as post-operative care following shoulder arthroscopy (Bankart repair). Our aim is to gain a better understanding of how to provide optimal post-operative care for patients and…
The primary aim of the study is to determine the effectiveness and cost-effectiveness of I-TFT versus S-TFT as a first-line treatment for PTSD in people with multiple traumas. Hypotheses are: (1) I-TFT is non-inferior to S-TFT in terms of…
The objective of this study is to investigate whether oral supplementation of citrulline will improve the amount of MSCs and osteogenic capacity in BMAC.