163 results
1.What is the long-term (24 weeks) effect of magnesium citrate (total daily dose: 450 mg elemental magnesium) on vascular stiffness measured from carotid-femoral pulse wave velocity (PWV) in healthy overweight and slightly obese men and women? 2. Is…
To test our hypothesis that vitamin K2 supplementation will induce a clinically relevant reduction in the degree of micro-calcification from carotid artery disease patients, when comparing to a placebo, after 3 months.
To compare the outcome of revascularisation the gastrointestinal arteries using covered stents compared to bare-metal stents in patients with CGI.
Our main goal is to establish whether there is difference in the effect between the use of aspirin, dualtherapy aspirin/clopidogrel, or ticagrelor on the occurrence of atherothrombotic events in patients following lower extremity peripheral…
Primary objective:- to compare the amount of contrast medium required to perform iliac/peripheral and EVAR procedures using the AlluraClarity control settings and the study settings, at similar procedure complexity, quantified as fluoro time, number…
The objective is to study the possible effects of AGE/ALE reduction on vascular function as primary endpoint, insulin sensitivity, and adipokine levels in abdominally obese subjects. We will investigate the following parameters:1) Micro- and…
The HemaTrate Blood Filtration System is commercially available and indicated for the rapid preparation of a TNC concentrate for use in human cell therapy applications. This study is designed to obtain the data needed to support a new, specific…
To provide an answer to the following questions: 1. In patients with AD, does treatment with a ChEI improve cerebral hemodynamics? 2. Is there less progression of cerebrovascular lesions on follow-up of AD patients receiving ChEI*s? 3. Does this…
The main objective is to investigate whether the additional use of IVUS leads to an increase in net lumen gain (NLG) when compared with standard angiography-guided endovascular treatment as measured during control IVUS after six weeks. Secondary…
To demonstrate superior efficacy and non-inferior safety of the SELUTION SLR 014 DEB compared to PTA (uncoated balloon) in the treatment of peripheral arterial disease (PAD) in the BTK arteries in CLTI patients.
The primary objective is to establish the non-inferiority of the Synergy stent relative to the Xience stent for prevention of MACE. The effect measure is the difference in the rate of MACE in patients randomized to treatment with the Synergy ( index…
The primary objective of this study is to investigate the effect of MK-7 supplementation on vascular stiffness in a subgroup of subjects with poor vitamin K status.For this follow-up study the primary objective is to investigate the correlation…
To gain more knowledge about the effects of SGLT2 inhibition on renal hemodynamics and the underlying mechanisms.
To evaluate the safety, including tolerability, of ISIS 681257 and to assess the efficacy of different doses and dosing regimens of ISIS 681257 for reduction of plasma Lp(a) levels in patients with hyperlipoproteinemia(a) and established CVD.To…
Primary objectives:*To determine whether rivaroxaban 2.5 mg twice daily (bid) + aspirin 100 mg once daily (od) compared with aspirin 100 mg od reduces therisk of a composite of myocardial infarction, stroke, or cardiovascular death in subjects with…
To quantify the change in hepatic fat (primary objective) and endothelial function, arterial stiffness, plasma lipids, plasma biomarkers of inflammation and endothelial function, and plasma advanced glycation end products (secondary objectives)…
To examine the impact of remote ischaemic postconditioning after an ischaemic stroke on infarct size and clinical outcome in patients, but also to better understand the potential underlying mechanisms contributing to these effects.
The primary aim of this study was to compare bloodless surgery using vascular clamps and a tourniquet with respect to the development of an anatomical or hemodynamic significant stenosis in patients with a brachiocephalic or radiocephalic AVF.
To explore the inflammatory changes of dapagliflozin compared with placebo on postprandial lipemia and postprandial leukocyte activation, oxidative stress and endothelial function in men with type 2 diabetes mellitus using insulin.
To assess the safety and efficacy of the paclitaxel drug-eluting balloon IN.PACT 014 versus conventional, optimal percutaneous transluminal angioplasty (PTA) for the treatment of patients with chronic total occlusions in the infrapopliteal arteries…