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Efficacy of routine elastic stockings after varicose vein surgery: a prospective randomised trial.

The main objective is to determine whether the post-operative application of elastic stockings after varicose vein surgery is useful to reduce post-operative pain. Secondly we want to determine whether there is a difference in physical functioning…

Comparative randomized clinical trial of Steam Ablation versus Endovenous Laser Ablation for the treatment of Great Saphenous Veins

To test whether the anatomical success rate of Steam Ablation is not inferior to that of EVLA in treatment of GSV insufficiency and compare the treatment related complications, patient reported outcomes and cost-effectiveness analyses between EVLA…

A randomised trial on communicating evidence with a decision aid in abdominal aortic aneurysm surgery: improving informed decision making in patients and surgeons

In this study, the effect of a decision aid regarding the choice between watchful waiting or surgical treatment of AAA is explored, regarding decisional conflict, knowledge, satisfaction, quality of life, anxiety and clinical endpoints.

A Randomized multicenter clinical trial of Unruptured Brain AVMs

Primary: To determine whether medical management improves long-term outcomes of patients with unruptured BAVMs compared to invasive therapy (with endovascular procedures, neurosurgery, or radiotherapy, alone or in ombination). The trial has been…

Exercise versus angioplasty for claudication based on iliac artery lesion

Primary objective of this study is to assess the treatment outcomes in terms of mobility parameters.Secondary objective is to assess the level of functional status and health-related quality of life.

The Impact of Intraoperative Carbon Dioxide Wound Ventilation on Cerebral Microembolic Load during Aortic Arch Surgery : a Prospective Randomized Clinical Trial using Transcranial Doppler Ultrasound

The primary objective of this study is to evaluate the impact of carbon dioxide field flooding on the quantitative intraoperative microembolic load of the brain during aortic arch surgery.A secondary objective is to evaluate any concomitant…

Clopidogrel for the prevention of late cardiac events in patients with asymptomatic perioperative acute coronary syndrome.

The primary objective of this study is to determine whether clopidogrel + best medical treatment is superior to best medical treatment only in preventing:A) cardiovascular death, MI, stroke, or severe ischemia of the coronary or peripheral arterial…

VESPA Trial: Endovenous laser treatment versus crossectomy of the small saphenous vein.

This randomized trial will compare EVLT with saphenopopliteal ligation with regard to therapy failure (a) and recurrence (b). a. Insufficiency of the SSV determined by ultrasound 6 weeks post-treatment is regarded as a therapy failure. b.…

Haemorrhoidal Artery Ligation Study: the surplus value of the Doppler

The objective is that 6 standard ligation of hemorrhoidal arteries is as effective as doppler guided.

Randomized Evaluation of dabigatran etexilate Compared to warfarIn in pulmonaRy vein ablation: assessment of an uninterrupted periproCedUral alntIcoagulation sTrategy (The RE-CIRCUIT Trial)

See section 2.2. of the protocol.The primary objective of this trial is to assess the safety of an uninterrupted dabigatran etexilate periprocedural anticoagulant regimen compared to an uninterrupted warfarin regimen in NVAF patients undergoing AF…

An international, multicenter, randomized, double-blind, placebocontrolled
phase 3 trial investigating the efficacy and safety of rivaroxaban
to reduce the risk of major thrombotic vascular events in patients with
symptomatic peripheral artery disease undergoing lower extremity
revascularization procedures

The primary efficacy objective of the study is:* to evaluate whether rivaroxaban added to ASA is superior to ASA alone in reducingthe risk of major thrombotic vascular events (defined as MI, ischemic stroke, CVdeath, ALI, and major amputation of a…

Catheterization of the radial artery with fixated ultrasound transducer

Primary Objective: Investigate whether fixation of the ultrasound probe, thereby freeing both hands for needling, improves performance of radial artery punctureSecondary Objective(s): Investigate whether fixation of the probe will lead to decreased…

PROTECTED TAVR: Stroke PROTECTion with SEntinel During Transcatheter Aortic Valve Replacement

The objective of this study is to demonstrate that use of the Sentinel® Cerebral Protection System significantly reduces the risk of periproceduralstroke (*72 hours) after transcatheter aortic valve replacement (TAVR).

Deferoxamine in Aneurysmal Subarachnoid Hemorrhage trial

This study has been transitioned to CTIS with ID 2024-514615-10-01 check the CTIS register for the current data. This study investigates the effectivity and the safety of deferoxamine use in patients with aneurysma subarachnoidhemorrhage.

A preoperative program to promote peri- and postoperative health in patients undergoing thoracic aortic surgery: a randomized controlled trial.

To compare the effects of a preoperative PA program in addition to usual care versus usual care only on the change in SB from baseline (T0) to the end of the preoperative (intervention) period (T1) in patients with TAD.

A Randomized Trial comparing the Drug-Eluting Stent (DES) Below-the-Knee (BTK) Vascular Stent System (DES BTK Vascular Stent System) vs Percutaneous Transluminal Angioplasty (PTA) Treating Infrapopliteal Lesions in Subjects With Critical Limb Ischemia

Primary objective: To demonstrate a superior patency rate and acceptable safety rates in below the knee arteries with lesions treated with the DES BTK Vascular Stent System vs percutaneous transluminal angioplasty. (PTA). Secondary objective: To…

Optimizing Access Surgery In Senior hemodialysis patients

To compare surgical strategies for vascular access creation in elderly hemodialysis patients.

Multicenter Randomized CLinical trial of endovascular treatment for acute ischemic stroke in the Netherlands. The effect of periprocedural MEDication: heparin, antiplatelet agents, both or neither.

To assess the effect of acetylsalicylic acid (ASA) and unfractionated heparin, alone, or in combination, in patients with AIS, who undergo IAT for a confirmed intracranial anterior circulation occlusion.

The effects of branch pulmonary artery stenting in d-TGA, ToF and TA: a randomized control trial

The primary study objective is to identify the effects of percutaneous interventions for branch PA stenosis on exercise capacity in patients with d-TGA, ToF and TA. The secondary objectives are 1) to assess the effects of percutaneous interventions…

Randomized controlled clinical trial on the application of Heli-FX EndoAnchors in conjunction with the Endurant II/IIs endograft in infrarenal aortic aneurysms with a wide infrarenal neck

The primary objective of this study is to investigate if the use of Heli-FX EndoAnchors in conjunction with placement of aortic stent grafts under instructions for use (IFU) conditions in aneurysms with a wide neck is superior to treatment with…