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A multicenter randomized controlled trial comparing long term scar quality after hydrosurgical versus conventional tangential excision of deep dermal burns

To assess and compare long term scar quality of deep dermal burns after debridement with hydrosurgical- and conventional tangential excision.

The treatment of moderate to severe onychocryptosis with either a wedge resection with or without phenolization or partial nailmatrix resection with phenolization, a randomized controled trial.

The objectification of the most effective surgical treatment, in which three operationprocedures are compared.

A pilot randomized controlled trial comparing the effect of a percutaneous and lipofilling technique in patients with a secondary Dupuytren*s contracture with standard fasciectomy surgery on convalenscence, contracture correction and recurrence rate.

To compare treatment of secondary Dupuytren*s contracture by standard limited (dermo)fasciectomy and by the modified percutaneous release combined with fat grafting. We focus specifically on return to function and if applicable to return to work (…

Recognising Effective Materials By Randomising & Assessing New Donorsite Treatments

This trial will compare the effectiveness and possible adverse effects of five common wound dressing materials to treat donor sites of split skin grafts.

A randomized study comparing Lichtenstein with ProGrip repair for primary inguinal hernias

Evaluation whether the use of the progrip mesh compared to the standard sutured mesh results in less chronic pain.

Gluteal turnover flap for closure of the perineal wound after abdominoperineal resection for rectal cancer, BIOPEX 2-study

The high morbidity rate of the perineal wound has resulted in a continuing discussion on how to close the perineal defect after APR. Our research group recently published the BIOPEX-study (NL42094.018.12), in which 104 patients were randomized…

Pilot study on robot-assisted microsurgical lymphatico-venular anastomosis

This pilot study assesses the performance of a robot-assisted microsurgery. Lympho-venular anastomosis(LVA) is the most difficult procedure in microsurgery at this moment. This LVA technique is applied to treat for example breast cancer related…

Gownless Hand Surgery Trial

: To investigate whether the omission of surgical gowns during CTR and TVR surgeries af-fects postoperative wound infections

Reducing Pain and Anxiety with Virtual Reality at the Emergency department, in children

Primary- Does the application of Virtual Reality (VR) reduce anxiety in patients undergoing treatment for traumatic injury in the emergency department compared to patients not using VR headset? Secondary- Does the use of Virtual Reality (VR) lead to…

Indocyanine Green for Perfusion Assessment of DIEP Flaps: A Dutch Multicenter Randomized Controlled Trial

To determine whether fluorescence imaging using ICG for the assessment of DIEP flap perfusion during surgery decreases the occurrence of fat necrosis compared to standard intraoperative clinical assessment of DIEP flap perfusion.

Effectiveness of Dermal Substitution and Negative Pressure Wound Therapy in Burns: a Randomized Controlled Pilot Study

To investigate the effect of a human-derived donor skin substitute Glyaderm when combined with negative pressure wound therapy in comparison to the gold standard treatment.

Surgical excision versus photodynamic therapy and topical 5-fluorouracil in treatment of Bowen*s disease: a multicenter randomized controlled trial

Primary Objective: To determine the (cost)effectiveness of 5-fluorouracil cream (5FU) and photodynamic therapy (PDT), compared to surgical excision (SE) in Bowen*s Disease (BD).Secondary Objectives: To determine the (cost)effectiveness of 5-…

Effect of Virtual Reality on treatment experience during surgical treatment of Carpal tunnel and trigger finger syndrome: a randomized controlled trial

Since Triggerfinger and Carpal tunnel syndrome are hand disorders most commonly presented at the outpatient clinic, the aim of our study is to investigate what the effect is of virtual reality use during wide awake local anesthetic tourniquet &…

Study protocol for a randomised clinical trial comparing TREPP versus Lichtenstein*s technique in Inguinal hernia patients

To asses the hypothesis that chronic postoperative inguinal pain occurs less in patients treated with the TREPP technique