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A pilot study on the effectiveness of the echoguided Transversus Abdominis Plane block during inguinal hernia repair surgery.

-The objective of this study is to determine, whether the use of an perioperative echo guided unilateral TAP block has an superior effect on postoperative pain after open hernia inguinal repair compared to wound infiltration with a long acting local…

Suture Techniques to reduce the Incidence of The inCisional Hernia

Primary question• Which bite size should be used to close a midline incision to prevent incisional hernia?Secondary questions• Is there a difference in postoperative complications between the two patient groups?• Is there a difference in…

A double-blind randomized controlled trial comparing PArietene self-fixing semi-Resorbable mesh with standard heavy-weight polypropylene mesh on chronic inguinal pAin DEvelopment

Primary:Does the implementation of a Parietene® self-fixing semi-resorbable mesh (Covidien-Sofradim) result in less chronic inguinal pain as compared to a standard polypropylene mesh (Marlex®; Bard) in the treatment of a inguinal hernia using the…

Tilburg double blind randomised controlled trial comparing inguinal hernia correction with anterior approach via Lichtenstein or Polysoft.

To compare postoperative pain after anterior inguinal repair with mesh according to Lichtenstein or open repair with Polysoft® mesh

Pre-incisional bupivacaine infiltration trocarincions, reduction of postoperative pain?

The purpose of this study is to monitor whether preicncisional bupivacaine (bupivacaïne 0,5% with epinefrine 1:200.000), infiltration in trocarcincisions reduces postoperative wound pain.

Pre-injection analgesic effects of low-level laser/light therapy (LLLT) in preparation for third molar surgery

The aim of this study is to evaluate the analgesic effects of LLLT on maxillary and mandibular block pre-injection sites in patients scheduled for elective third molar removal.

A randomised, double blind clinical trial comparison the effect of a ultrasound-guided transversus abdominis plane (TAP) block and wound infiltration on postoperative pain (48h) for open inguinal hernia repair in day-care

The objective of this study is to determine, whether the use of an perioperative echo guided unilateral TAP block has an superior effect onpostoperative pain after open hernia inguinal repair compared to wound infiltration with a long acting local…

A phase Ib/II randomized double-blind placebo controlled trial evaluating the effect of Nivolumab for patients with in-transit melanoma metastases treated with isolated limb perfusion (NivoILP trial)

This study has been transitioned to CTIS with ID 2023-509265-21-00 check the CTIS register for the current data. To evaluate safety and the effect of isolated limb perfusion together with nivolumab as a way to increase efficacy and give further…

Perioperative Lipofilling in Operative Treatment of Proximal Phalanx Fractures and Related Tenolysis: Improving Range of Motion

The aim of the two separate studies is as follows: 1. To evaluate the effect of perioperative micronised lipofilling in patients with ORIF of P1 fractures on postoperative range of motion2. To evaluate the effect of perioperative micronised…

The efficacy of botulinum toxin A injection in pelvic floor muscles in chronic pelvic pain patients: a double-blinded randomised controlled trial

The objective of this study is to investigate whether BTA injection in the pelvic floor muscle is an effective treatment for patients with chronic pelvic pain and pelvic floor hypertonicity.

Difference in pain and functional outcome after arthroscopic debridement vs. debridement and biodegradable implanted balloon for irreparable rotator cuff tears.

Primary Objective: • Is there a minimal clinical difference (NRS >2) in pain levels between subjects receiving an arthroscopic debridement with a subacromial bio-absorbable Balloon and solely arthroscopic debridement in subjects with…