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A phase III randomized study of preoperative radiotherapy plus surgery versus surgery alone for patients with retroperitoneal sarcoma (RPS)

To assess whether preoperative radiotherapy, as an adjunct to curative-intent surgery, improves the abdominal local recurrence-free survival.

A Phase 3, Randomized, Single-Blind, Controlled Trial of Topical Fibrocaps* in Intraoperative Surgical Haemostasis

Primary:The primary objective of the study is to demonstrate the superiority of Fibrocaps plus gelatin sponge, as compared to gelatin sponge alone, for achieving hemostasis in subjects undergoing spine, liver, vascular or soft tissue surgery, when…

Pre-incisional bupivacaine infiltration trocarincions, reduction of postoperative pain?

The purpose of this study is to monitor whether preicncisional bupivacaine (bupivacaïne 0,5% with epinefrine 1:200.000), infiltration in trocarcincisions reduces postoperative wound pain.

Clinical, microbiological and radiographical evaluation of implant surface decontamination using air polishing in the surgical treatment of peri-implantitis; a randomized controlled study

The primary objective of this randomized controlled trial is to compare the clinical effect of decontamination of the implant surface during the surgical treatment of peri-implantitis using air polishing or hand instruments. The secondary objective…

A randomized phase III study of neoadjuvant chemotherapy followed by surgery versus surgery alone for patients with High Risk RetroPeritoneal Sarcoma

This study has been transitioned to CTIS with ID 2023-505261-84-00 check the CTIS register for the current data. The primary objective of this study is to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves…

The efficacy of botulinum toxin A injection in pelvic floor muscles in chronic pelvic pain patients: a double-blinded randomised controlled trial

The objective of this study is to investigate whether BTA injection in the pelvic floor muscle is an effective treatment for patients with chronic pelvic pain and pelvic floor hypertonicity.

PROphylactic Mesh to prevent Incisional hernias at the former Stoma Site: the PROMISS-trial

To evaluate the incidence of incisional hernias after stoma reversal after preventive mesh placement compared to no mesh placement. Secondly the incidence of parastomal hernias will be recorded and complications caused by preventive mesh placement…