53 results
The primary research question of the trial is to assess whether foot drop, caused by peroneal nerve entrapment in adult patients* recovers better within 9 months after decompressive surgery compared to prolonged standard conservative treatment. *…
Evaluation of the (cost-)effectiveness of surgical decompression of compressed lower extremity nerves (LEND surgery) compared to patients 'treated' with conventional best care.
The aim of this study is to determine whether VR used during lumbar puncture will significantly reduce pain and anxiety perception.
1. To study whether minimally invasive endoscopy-guided surgery, in addition to standard medical management, for the treatment of spontaneous supratentorial ICH performed within 8 hours of symptom onset, improves functional outcome in comparison…
The primary objective is to demonstrate non-inferiority of MagnetOsTM Granules compared to autograft in instrumented posterolateral spinal fusion, in terms of efficacy and safety by means of an intra-patient model.
The study will take place in 5 neurosurgical centers in the Netherlands (Erasmus MC, UMC Utrecht, Elizabeth Ziekenhuis Tilburg, MC Haaglanden The Hague, UMCG Groningen) and one center in Belgium (UZ Gent). All centers have ample experience with the…
Overall ObjectiveThe purpose of the study is to compare the effect of craniotomy and tumor resection followed by adjuvant second-line therapy to no surgery followed by second-line therapy on overall survival, neurological status, and quality of life…
To document whether patients treated with minimally invasive surgery experience less back pain at 2 and 6 weeks after surgery, compared to patients treated with conventional open instrumented surgery.
To determine whether intraoperative epidural analgesia is superior to placebo in reducing wound pain in patients after decompressive lumbar spine surgery, and to determine whether opioid use in the 2 days after surgery is significantly higher in the…
The primary objective of this randomized controlled trial is to determine whether decompressive surgery and best medical treatment in patients with spontaneous ICH will improve outcome compared to best medical treatment only. Secondary objectives…
In this pilot study, we aim to assess practical feasibility, technical feasibility and safety of a computational approach for programming newly implanted STN-DBS patients with PD. This computational approach will be based on patient-specific sweet…
To evaluate the safety and efficacy of ReActiv8 for the treatment of adults with Chronic Low Back Pain and no prior spine surgery when used in conjunction with medical management.
The objective of this study is to determine the value of TOD (first rib resection with partial scalenectomy and neurolysis) on functionality and quality of life. We will do this by randomizing patients into who already received physiotherapy into…