35 results
The purpose of this study is to determine whether early intervention with subcutaneous (s.c.) secukinumab 300 mg in patients with new-onset moderate to severe psoriasis may lead to prolonged symptom-free periods by preventing reactivation of old…
The main objective of this study is to investigate the effect of a topically applied emollient enriched with barrier lipids on the barrier properties of skin of AE patients.
To evaluate the additional effect of coal tar treatment to a corticosteroid regimen in adults (aged >16 years of age) with moderate to severe atopic dermatitis, based on the percentage change in Eczema Area and Severity Index (EASI) at week 2…
Assessing the value of SunshowerMedical Helios as a at home maintenance treatment for patients with psoriasis vulgaris.
A randomised controlled multcenter trial is performed to evaluate the perforator-based interposition plasty in comparison to full thichness grafts for scar contracture releases.
The primary research question is:Do children with atopic dermatitis and asthma after a stay in the NAD have a better coping and acceptance of their disease as compared with children treated at the outpatient department of the WKZ?Secondary research…
To evaluate the effectiveness, cost-effectiveness and quality of life of Flaminal® versus Flammazine® in the treatment of superficial and deep partial thickness burns.
Primary Objectives-To compare the efficacy responses of CP-690,550 (5 mg BID and 10 mg BID) versus placebo following 24 weeks of CP-690,550 treatment and subsequent withdrawal of active treatment at various timepoints during the 16-week double-blind…
This study will establish the role of surgical versus nonsurgical approaches in patients whose melanoma has spread to distant sites. Results will help clinicians develop a standardized initial approach that prolongs survival and optimizes quality of…
There are indications that early laser treatment of wounds can reduce scar formation. With the laser device the wound will be heated, which is thought to be responsible for a reduced inflammatory reaction and hence for a reduced scar formation. The…
To gain insight in the effects and cost-effectiveness of the introduction of laser Doppler imaging in burn care.
The primary objective of this research is to compare pain experience and comfort when a calcium alginate or Suprathel® is used on the donor site. Secondary objectives are the differences in scarring, itching of the scar tissue and costs involved…
This research aims to conduct blistering and reduce freguent dressing changes in patients undergoing total hip replacement or total knee replacement have undergone in the use of Aquacel Surgical dressing.This compares with the usual method of wound…
The objective of the study is to assess the value of the *Topical Treatment Optimising Programme* in the topical treatment, which will be use together with the standard treatment, of insufficiently treated mild to moderate psoriasis after 8 weeks of…
The research question of the underlying study is: What are the effects of GMA*s on children with atopic dermatitis/ food allergy and their parents as compared with individual visits on:- physical complaints- self management- quality of life
Objective: The primary objective is to investigate whether sensitive skin fundamentally differs from *normal skin*. In this study, we try to identify the morphological and functional characteristics of sensitive skin by provocation of the skin with…
The most important objective from this investigation is to prevent or substitute the damage which is coused by therapeutical radiation. As it's most likely that the skin damage as a result of therapeutical radiation can be more limited. From…
A randomised controlled trial is performed to evaluate the clinical effectiveness of the skin stretching technique for two categories:a. acute burn wounds: wound closure by means of skin stretching should lead to a significant reduction of scar…
The objective of this study is to assess the safety and efficacy of efalizumab combined with methotrexate compared with efalizumab monotherapy in adult patients (aged > 18 years) with moderate to severe psoriasis.
Aim of the study is to investigate if application of a dermal substitute in combination with topical negative pressure can improve the quality of the scar in burn wounds.