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A phase 2 multicentre randomized controlled comparative efficacy and safety study of Tiscover and AS210 in chronic (arterio-)venous ulcers

Determine the safety and efficacy of Tiscover compared to AS210 (acellular donor dermis, construct Tiscover is cultured on) for the treatment of chronic, therapy resistant (arterio-) veneus leg/foot ulcers in an out patient setting.

Prospective study to the Optimal duration of Compression Therapy As prevention of chronic Venous Insufficiency After deep venous thrombosis

ACT reduces the incidence of PTS after DVT. In the Dutch CBO-guidelines current therapy is adviced for 2 years after diagnosis because most PTS develops within 2 years after DVT, with a peak incidence in the first year.Some clinicians claim that one…

Protocol for the clinical evaluation of wounds after topical administration of OTR4120 to ulcers.

To validate that OTR4120 will improve the healing of chronic ulcers.

An open randomised comparative study to evaluate the performance of AQUACEL® Extra* in Venous Leg Ulcers

The primary objective of the above study is to evaluate the wear time AQUACEL® Extra* when compared to AQUACEL® in subjects with venous leg ulcers. Stratification will be done for exudate (moderate vs highd) and type of dressing (AQUACEL®Extra*…

Comparative randomized clinical trial of Steam Ablation versus Endovenous Laser Ablation for the treatment of Great Saphenous Veins

To test whether the anatomical success rate of Steam Ablation is not inferior to that of EVLA in treatment of GSV insufficiency and compare the treatment related complications, patient reported outcomes and cost-effectiveness analyses between EVLA…

Randomized controlled clinical study to assess the clinical efficacy of the 3M* Coban* 2 Layer Compression System compared to a short-stretch compression bandage in the treatment fo venous leg ulcers

The objective of the study is to evaluate the clinical efficacy of 3M* Coban* 2 Layer Compression System in the treatment of venous leg ulcers compared to Rosidal® K shortstretch compression bandage (Lohmann & Rauscher, Rengsdorf, Germany).

Modified treatment of port wine stains with the pulsed dye laser: a randomised controlled trial

The primary objective of this study is to assess the efficacyand safety of modifications of the laser treatment to increase the clearance of port wine stains.

The additional effect of SW 112 (wound irrigation solution) combined with regular wond treatment on the bacterial load of chronic foot ulcera: a pilot randomized controlled trial

Het wetenschappelijk onderzoek naar de meerwaarde van SW 112 op bacteriën/biofilm bij de behandeling van chronische voetulcera staat nog in haar kinderschoenen. Daarom is het doel van het onderhavige onderzoek om meer inzicht te krijgen in de…

Does Applying More Oxygen Cure Lower Extremity Sores?

To assess the relative effectiveness of HBOT as an adjunct to standard wound care in terms of preventing amputations and improving wound healing in ischemic diabetic ulcers, and its cost-effectiveness. Secondary objectives are to assess the patients…

A randomized controlled trial testing hyaluronic acid spacer injection for skin toxicity reduction of Permanent Breast Seed Implant (PBSI)

The primary objective is to evaluate and report the effect of an injected hyaluronic acid spacer on the rate of telangiectasia following PBSI.

The effect of psychological intervention on the quality of life and wound healing in patients with diabetic foot ulcer

The aim of this study is to evaluate the effect of psychological intervention on the quality of life and wound healing in patients with a foot ulcer.

A Prospective Randomized Multicenter Single Blinded Study to Assess the Safety and Effectiveness of the SELUTION SLR* 014 Drug Eluting Balloon in the Treatment of Below-the-Knee (BTK) Atherosclerotic Disease in Patients with Chronic Limb Threatening Ischemia (CLTI)

To demonstrate superior efficacy and non-inferior safety of the SELUTION SLR 014 DEB compared to PTA (uncoated balloon) in the treatment of peripheral arterial disease (PAD) in the BTK arteries in CLTI patients.