8 results
This research project aims to determine the feasibility of setting up a randomized controlled trial to study the effects of different fluid management protocols on the outcome of mechanically ventilated pediatric patients with acute infectious lung…
A previous study of from our laboratory showed that administration of the drug C1-INH (100E/kg) significantly reduced the concentration of circulating pro-inflammatory cytokines, such as IL-6, in healthy male volunteers during human experimental…
The primairy goal of the current study is to investigate the effect of enriched nutrition on systemic levels of TNF-alpha.The secundairy goal is to investigate the effect of enriched nutrition on other markers of inflammation, splanchnic perfusion…
Does antagonism of the adenosine receptor by caffeine lead to an increased LPS-induced inflammatory reaction and an increase in (subclinical) tissuedamage?Does the C34T-polymorphism of the enzyme AMP-deaminase lead to a decreased inflammatory…
to study the effect of pre-treatment with the specific a7nAChR agonist GTS-21 on cytokine production and the effects on the subsequent subclinical organ dysfunction in the human endotoxemia model. to measure the effect of LPS administration in the…
To assess whether a self-administered intervention to promote the formation of Implementation Intentions successfully promotes the use of condoms in both lower and higher risk clients of an STI clinic and reduces the well-known discrepancy between…
The aim of this study is to evaluate if IV albumin administration improves short-term survival in patients with advanced cirrhosis (serum creatinine * 1.2 mg/dl, serum sodium * 130 mEq/l and/or serum bilirubin *4 mg/dl), signs of systemic…
The aim of our study is to investigate whether NPWT in closed incisional wounds decreases the rate of SSI, in patients undergoing laparoscopic or open colorectal surgery with a minimal incisional length of 30mm. Primary Objective: The primary…