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Implementing Treatment Algorithms for the Cure of Trauma Induced Coagulopathy (iTACTIC)

The primary objective is to compare the haemostatic effect of VHA-guided transfusion strategy versus optimized CCT guided transfusion strategy in haemorrhaging trauma patients. The secondary objectives of the study are to determine the effects of…

Chronic post-sternotomy pain, relation between accompanying painsymptoms and painlocation on the sternum

The objective of this study is to prove that chronic post-sternotomy pain is not a local painproblem, but part of a general painsyndrom.Our hypothesis is twofold:1. The investigated painsymptoms are of more frequently occurrence in the pain-sample…

Evaluation of the skin window technique in patients with complex regional pain syndrome

The current study aims to gain better insight into the pathophysiology of the aberrant inflammatory response in CRPS. The evaluation of the role of pro-inflammatory and anti-inflammatory mediators in response to a microtrauma may generate important…

The effect of intravenous lidocaine to prevent intracranial pressure increase in endotracheal intubation assessed by optic nerve sheath diameter

Primary Objective: To investigate the effect on the distention of the ONSD while using lidocaine 1,5 mg/kg IV during endotracheal intubation versus placebo. Secondary Objectives: The secondary objective of this study is to investigate the effect…