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Multimodal treatment of perianal fistulas in Crohn's disease: seton vs anti-TNF vs advancement plasty

Currently, there is no guideline for the treatment of perianal Crohn's fistulas. the aim of this study, in which surgical strategies (seton drainage and surgical closure with advancement plasty/LIFT) will be compared to medical treatment. We…

Use of platelet rich plasma(PRP) as an adjunct in the treatment of high peri-anal fistulas.

Objective: the use of autologous platelet rich plasma (PRP) as an adjunct to the staged mucosal advancement flap to achieve a better closure rate of high peri-anal fistula*s.

Pelvic floor therapy in the treatment of all anal fissures; a multicentre, randomized controlled trial

To assess the potential benefit of pelvic floor therapy for anal fissure. Measured primarily in pain, measured by the VAS score. Secondary outcomes are healing rates and recurrence.

LITA trial: A randomized controlled trial of ligation of the intersphincteric fistula tract versus transanal advancement flap repair

Aim of the present study is to investigate whether LIFT or TAFR is the preferable treatment for high transsphincteric fistulas-in-ano of cryptoglandular origin.

Anal cooler for anal pain

to investigate the clinical effects of the Anal Cooler

Pelvic Floor Physiotherapy in chronic anal fissure

Efficacy of treatment with biofeedback assisted pelvic floor physiotherapy using electromyography (EMG) in patients with chronic anal fissure.

Comparing Minimally Invasive Treatments for Pilonidal Disease: LA POPA trial (Laser And Pit-picking OR Pit-picking Alone)

The main objective of this study is to establish the efficacy of *pit picking with laser therapy* versus *pit picking alone* on both short and long-term outcomes.