15 results
To investigate whether the extent to which patients adhere to the Dutch dietary guidelines improves more in out clinic patients, with a positive iFOBT, who receive dietary and physical activity advice by the Eetscore during 3 months, than in out…
Our primary objective is to study the effect of perioperative intravenous supplementation of omega-3 fatty acids on the perioperative inflammatory response compared to a saline control in patients undergoing surgery for colon cancer.
The purpose of this project is to perform a randomized trial comparing BARRX ablation with endoscopic surveillance for patients with a Barrett*s esophagus containing low-grade dysplasia. This study will also assess the effect of RFA ablation in…
Primary objective:To determine the relationship of route of gastroenteric anastomosis after PD and postoperative incidence of DGE.Secondary objectives:To determine the relationship of route of gastroenteric anastomosis after PD and gastric emptying…
Goal is to use two non-invasive techniques (continuous cardiac output monitoring and impedance measurement) to investigate the possibility of cardiac output measurement and impedance measurement to reduce the fluid intake with 30% reduction while…
Through a non-invasive cardiac output measurement we want to investigate in this observational pilot study , if it is possible to reduce the fluid intake in the first 24 hours (both perioperatively and postoperatively) by 30 %
To investigate whether stem cell sparing radiotherapy results in a lower risk of dry-mouth syndrome than current standard treatment technique.
The primary objective is the safety and feasibility of CEA/frameshift derived neopeptide loaded DC in patient with MSI-positive colorectal cancer and persons who are known to be carrier of a germline MMR-gene mutation with no signs of disease yet.…
The goal of this study is to prove that there is a benefit in terms of post-operative outcome not only because of the multi-modal improvements in peri-operative fluid management through the ERAS program, but also by the use of a goal-directed fluid…
The objective of this trial is to compare time to gastrointestinal recovery after elective colorectal surgery between patients treated with a laxative versus patients treated with a placebo.
To investigate whether prophylactic clipping (PC) after endoscopic mucosal resection (EMR) of a flat polyp in the colon prevents delayed bleeding (DB) and is cost-effective.
This study has been transitioned to CTIS with ID 2024-510766-16-00 check the CTIS register for the current data. This trial evaluates the additional value of pre-emptive antibiotic treatment on clinically relevant OSIs in patients undergoing…
The main objective of this study is to investigate whether intraoperative music reduces postoperative pain in patients undergoing surgery for esophageal or stomach cancer. Secondary objectives are the effects of intraoperative music on…
This study has been transitioned to CTIS with ID 2023-509360-24-00 check the CTIS register for the current data. Primary objectives: This study has co-primary objectives:• To compare OS of nivolumab versus placebo in subjects with resected EC or GEJ…
The aim is to determine the effectiveness of adjuvant HIPEC using oxaliplatin following a curative resection of a pT4 or intra-abdominally perforated colon cancer in preventing the development of PC in comparison to the standard adjuvant systemic…