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The effect of standard mindfulness based stress reduction (MBSR) on quality of life and symptom severity in patients with irritable bowel syndrome.

The research questions this study aims to answer are: What is the effect of a Mindfulness Based Stress Reduction (MBSR) training on IBS in terms of quality of life. It is hypothesised that participation in a MBSR-training will improve quality of…

Effect of domperidone and omeprazole in gastro-oesophageal reflux disease in infants between 0 and 2 years.

To measure the effect of domperidone and omeprazole on reflux-time, duration, and symptoms of GERD

Fecal calprotectin guided referral strategy in children in primary care

Point of care testing with Fcal POCT will reduce substantial the referral rate of children with chronic GI symptoms to the paediatrician.

Consumer Survey Mexico

The different processing of formulas will have an effect on stool characteristics such as consistency, frequency, amount and colour.

Hypnotherapy through self-exercises in children with functional abdominal pain
in primary care

To determine the (cost)-effectiveness of home-based hypnotherapy by self-exercises added to usual care (UC) of general practitioners (GPs) compared with UC of GPs alone in children with FAP or IBS.

HELIOS-A: A Phase 3 Global, Randomized, Open-label Study to Evaluate the Efficacy and Safety of ALN-TTRSC02 in Patients with Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)

This study has been transitioned to CTIS with ID 2023-508365-33-00 check the CTIS register for the current data. To determine the efficacy of ALNTTRSC02 in patients with hATTR amyloidosis by evaluating the effect on neurologic impairment. To…

Toddlers receiving synbiotics after antibiotics

To investigate the effect of a cows-milk-based formula supplemented with synbiotics from t=0 to t=21, t=42 and t=84 days after amoxicillin or amoxicillin/clavulanic acid treatment in toddlers aged 1, 2 and 3 years old on: - change in proportion of…

Effect of an immune-supportive diet on gut permeability and allergic symptoms in children with peanut and/or nut allergy.

Therefore, the purpose of our study is to study, in peanut and nut allergic children:1. the relationship between gut permeability and threshold levels to peanut or nuts;2. the effect of an immune-supportive diet on gut permeability, coexisting…

Face-to-face versus online hypnotherapy for the treatment of Irritable Bowel Syndrome, according to a non-inferiority design. Three-armed randomized controlled trial. (FORTITUDE)

Primary objective:To compare the efficacy of online hypnotherapy versus face-to-face according to a non-inferiority design for the treatment of IBS.Hypothesis: Hypnotherapy delivered in the form of online exercises has non-inferior efficacy to face-…