70 results
Primary Objective(s): 1. To obtain preliminary data on whether (and to which extend) adjuvant chemotherapy for colon cancer results in (a) deterioration of contractile muscle properties and increased muscle fatigability, (b) increased inflammation…
We have developed the TES program, which involves Targeted selection and Enhanced care, delivered on the basis of Stepped care (TES). The primary study aim is to evaluate the effectiveness of the TES-program compared to usual care in reducing…
To study the effect of individualized nutritional counselling compared to usual nutritional care on cross-sectional muscle area in patients with stage IV colorectal cancer during first-line chemotherapy. Secondary, effect on total lean body mass,…
- Primary study objective: To demonstrate the superiority of the ablative microboost dose schedule regarding 5-year biochemical no evidence of disease rate compared to the current standard of care.- Secondary study objectives: Establish and compare…
The UPGRADE-RT trial will investigate whether de-escalation of the elective radiation dose and introduction of an intermediate dose-level in the treatment of head and neck cancer will results in less radiation sequelae and improved quality of life…
The purpose of the proposed project is to evaluate the immediate and long-term effects of cognitive rehabilitation in a prospective randomized trial on neuropsychological test performance and self-reported cognitive symptoms, psychological symptoms…
To investigate whether raw milk, pasteurized milk or ultra-heat treated (UHT) milk is able to enhance the systemic immune response as induced by oral cholera vaccination, in comparison to regular vaccination. Oral vaccination can also induce an…
To compare the HM to bipolar resectoscopy for removal of large intrauterine polyps in terms of efficiency and complications.
The aim of this study is to accelerate recovery after liver surgery by enhancing intestinal passage through the preoperative use of Movicol®.
The aim of the current study is to examine the (cost)effectiveness of Mindfulness Based Stress Reduction (MBSR) in comparison with treatment as usual for patients with lung cancer and their partners.
The objective of this study is to investigate effects of different forms of patient information on chemotherapy side effects, in particular, assessing the severity and duration of the negative effects of information on chemotherapy-associated…
The number and severity of adverse drug reactions (renal function, nausea and tremor) of cyclosporine using AUC targeted Therapeutic Drug Monitoring as compared to C0 targeted TDM.
In this study, we aim to improve recognition of delirium in a palliative care population with advancedcancer and we aim to provide evidence for optimal treatment of delirium through adequate dosing ofpreferred neuroleptic.Primary objectives:1) To…
The objective of this pilot randomized controlled trial (RCT) is to assess the feasibility and to determine the effect size of a physical activity/exercise program in improving objective cognitive functioning and reducing self-reported cognitive…
Evaluation of the cosmetic result after 12 months of transcutaneous sutures versus intracutaneous sutures in the craniofacial area.
Primary Objectives:This study consist of:1) a prospective cohort study in which all patients with esophageal cancer, selected for esophagectomy, and willing to be included in this cohort, are followed to assess their complications, short en long…
The primary objective of this study is to compare a semi-mechanical with a hand sewn cervical anastomosis after esophagectomy with gastric tube reconstruction for cancer.
(1) To evaluate the effectiveness of an individualized exercise program in comparison to standard care with respect to fatigue, physical fitness and health-related quality of life in patients with hematologic malignancies who have undergone HDC and…
To reduce intraoperative blood loss and enhance tolerance of the FRL to I/R injury during right hemihepatectomy under vascular exclusion by means of in situ hypothermic perfusion with retrograde outflow (R-IHP) of the FRL.
Primary objective:To determine the relationship of route of gastroenteric anastomosis after PD and postoperative incidence of DGE.Secondary objectives:To determine the relationship of route of gastroenteric anastomosis after PD and gastric emptying…