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Effect of the addition of pre-biotics to infant formula on markers of immune development and atopy at 5 years of age

are there differences in levels of IgE and sub-classes, TARC ,light chain IgG and titers against vaccins HiB and Tetanus between children who received as infant a formula with or without pre-biotics ?

The role of the gut MIcrobiota in the SyStemic Immune respONse during human endotoxemia

To investigate the role of the gut microbiota in the systemic priming of immune effector cells during human endotoxemia

Consequences of liver surgery for liver function and cell injury

1 Primary Objective To investigate the effects of 15* liver ischemia versus 30* liver ischemia on liver injury and liver function.To investigate the effect of liver manipulation during mobilisation for a right hemihepatectomy, that can be used as a…

Insertion of a central venous catheter through a tegaderm as a preventive measure against catheter colonization and infection

Primary: Investigate if sterile transparent dressing pasted on the skin before CVC insertion reduces the contamination risk of the CVC.Secondary: Investigate if direct contamination has a clinical significance.Investigate what the mayor…

Consequences of early-life antibiotic exposure on antimicrobial gene selection: what regimen causes least harm?

Primary Objective: 1) To assess the short- and long-term prevalence of AMR genes in the microbiome of the gut in infants exposed to broad-spectrum antibiotics in the first week of life compared to controls. 2) To investigate the short- and long-term…