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Comparison of monocular implantation of the Acrysof Toric T2 intraocular lens with a standard monofocal intraocular lens in subjects with cataracts and low corneal astigmatism

- Analyse the effect of the toric T2 intraocular lens on quality of vision, compared to a standard monofocal intraocular lens. - Analyse the satisfaction of patients with their visual acuity with the toric T2 intraocular lens, compared to a standard…

Bioavailability of lutein from a lutein-enriched egg-yolk-beverage and its dried re-suspended versions.

The primary objective of this study is to investigate whether consumption of a dried lutein-enriched egg-yolk containing beverage significantly increases serum lutein concentration in healthy volunteers.A secondary objective is to investigate…

A Phase 3 Randomized, Double-Masked, Placebo-Controlled Study of the Pharmacokinetics of OMS302 and the Effect of OMS302 on Intraoperative Pupil Diameter and Early Postoperative Pain in Subjects Undergoing Intra Ocular Lens Replacement with Phacoemulsification.

The co-primary objectives of this study are to evaluate the effect of OMS302 compared to placebo when administered in irrigation solution during phacoemulsification and intraocular lens replacement on: • Intraoperative pupil diameter.• Pain during…

VERION vs conventional, manual ink-marking in toric IOL implantation

The primary objective of the study is to compare the accuracy in toric IOL alignment when using the VERIONTM Measurement Module and VERIONTM Digital Marker for alignment of the toric IOL or the conventional manual ink-marking procedure. The…

A randomised, subject-masked evaluation of visual function after bilateral implantation of two types of presbyopia-correcting multifocal intraocular lenses (IOLs): the Symfony-study

Primary Objective: The primary objective of this study is to compare the postoperative visual outcomes in a series of patients bilaterally implanted with the AT LISA tri 839MP IOL versus those bilaterally implanted with the TECNIS® Symfony IOL (…

Effectiveness of customized corneal crosslinking versus standard corneal crosslinking in patients with progressive keratoconus

The objective of this project is to evaluate whether the effectiveness of customized cross-linking (cCXL) is non-inferior to the standard cross-linking protocol (sCXL).

A Phase 3, Multicentre, Double-masked, Randomised Study to Evaluate the Efficacy and Safety of Intravitreal OPT-302 in Combination with Aflibercept, Compared with Aflibercept Alone, in Participants with Neovascular Age-related Macular Degeneration (nAMD) (COAST)

This study has been transitioned to CTIS with ID 2024-512880-30-00 check the CTIS register for the current data. To determine the efficacy of intravitreal 2.0 mg OPT-302 when administered in combination with intravitreal 2.0 mg aflibercept, in…