112 results
Specific AimsAs reviewed above, childhood anxiety disorders are highly prevalent and debilitating, and there is an urgent need for improvement of current treatment strategies. An innovative, but scarcely examined, treatment option for childhood…
PRIMARY OBJECTIVE· 1. To study the effect of escitalopram versus placebo in the treatment of abdominal pain, in IBS patients with panic disorder.SECONDARY OBJECTIVES· 2.1. To assess the effect of escitalopram on gastrointestinal and psychiatric…
The aim of this research project is to investigate cannabidiol as a new medicine to target the cannabinoid system in the reduction of anxiety disorder symptoms. The research question is whether cannabidiol, as an augmentation strategy of exposure…
To investigate the efficacy of testosterone enhanced exposure therapy for social anxiety disorder.
The study aims to answer the following research questions:1. How high/low are levels of symptomatology of depression and/or PTSD in traumatised refugee children in ASC?2. Do symptom levels decrease after a short-term trauma-focused intervention?3.…
This study is aimed at assessing the effect of 3MDR treatment as compared to treatment as usual (TAU) on PTSD symptom severity in treatment resistant veterans with chronic cr-PTSD. It is expected that 3MDR will give a boosting effect to TAU…
The primary objectives of this study in healthy subjects are:- To investigate the safety and tolerability of JNJ-61393215 versus placebo after single oral dose administration under fasted (ascending dose levels) and fed condition.- To characterize…
This cost-effectiveness study will compare blended cognitive behavioral treatment (bCBT) with standard face-to-face CBT (CBT-TAU) among patients with a diagnosis of an anxiety disorder referred to an outpatient specialized mental health care. The…
The current study aims to replicate the Bohus study published in 2013, comparing the effect of a 12-week residential DBT-PE program on the severity of PTSD to that of a waiting list condition in patients who suffer from CSA related PTSD and from one…
The randomized controlled trial (RCT) will be performed at Karakter Child and Adolescent*s Psychiatric Hospital and will be implemented at all locations, spread out over three provinces in The Netherlands. The project aims:1. To explore the…
The aim of this study is to determine the effects of propranolol on patients* crucial fear-related memories and dental trait anxiety in those undergoing surgical removal of one of their teeth or molars. The hypotheses that are tested are that…
We want to answer the following research questions:- Which of the mentioned treatment approaches is more effective for improving self-esteem?- Do both approaches have additive value (does a patient benefit more after receiving both treatments, in…
The current proposal aims at investigating the effect of a multidisciplinary non-verbal intervention on the awareness and modulation of WRA to improve self-efficacy, mobility, mood, and quality of life as compared to usual care.
To test the effectiveness of the psychotherapy "Seeking Safety" in a Dutch SUD sample.
a. By this research a treatment protocol for NET will be quantitatively and qualitatively evaluated on its effects. b. With the research findings it is possible to identify subgroups within the research population and indicate who benefits most from…
Objective: The primary aim of the present study is to investigate the effectiveness of MBCT in a group format versus TAU in a group format for treatment refractory anxiety disorders Furthermore; we will investigate mediators associated with…
The current study aims at investigating whether individual mindfulness-based cogntiive therapy (MBCT) online and MBCT offered face-to-face in groups are superior to a waiting list-control group in terms of improvement of depression and anxiety,…
Investigation of the effect of interpretive bias modification on anxiety levels in dental phobia. If CBM-I indeed has positive effects in the treatment of dental phobia, it could be integrated in the treatment-as-usual as an additional intervention…
This study will examine the efficacy of this Virtual Reality Exposure Therapy (VRET) in a CSA and war related trauma sample by comparing it with treatment as usual (TAU). It will also attempt to develop protocols to implement this new technology…
Objective: The main objective is to evaluate the effectiveness of the POPP-treatment program in reduction of severity of post-traumatic stress symptoms for sexually abused preschoolers. Secondary objectives are to evaluate the effectiveness of the…