172 results
In the light of the aforementioned the current study has three objectives: 1) to study the effectiveness of an in-home self-management intervention to reduce fear of falling, avoidance behavior, catastrophizing about falls in order to prevent…
The first aim of the study is to investigate whether DCS addition to exposure therapy enhances symptom reduction in PD+AGO. The second objective of the study is to establish the optimal timing of administration of DCS (30 minutes before or directly…
The primary objective is to investigate whether a brief (10+2 sessions) Cognitive Behavioural Therapy (CBT) program can (postpone or) prevent the onset of depression or anxiety disorder in an ultra high risk sample of 8-18 year old children of…
Primary objective of the study is to test the effectiveness of two interventions (by comparison with a control intervention and by mutual comparison) in preventing the negative effects of critical incidents and chronic job demands on the outcomes:…
The main objective of the study is to determine whether, and if so, to what extent, there are differences in memory vividness, detail and certainty between OCD patients, another anxiety disorder patients and healthy subjects in a repetitive checking…
The aim of this study is the comparison of Mindfulness Based Stress Reduction (MBSR), with an empirically proven effective treatment, namely Cognitive Behavioral Therapy (CBT) in the treatment of panic disorders with or without agoraphobia.
Study ObjectiveTo determine whether alprazolam, a registered anxiolytic non-selective benzodiazepine, can reduce the autonomic temperature increase induced with social stress in healthy men. Secondary objectives are to determine whether alprazolam…
To determine the efficacy and safety of memantine for patients with OCD.
To contribute to the improvement of mental health care to traumatised asylum seekers and refugees.
-To test the efficacy and determine the costs of a multifaceted intervention program to reduce falls incidence rate and fear of falling, and thereby improve mental wellbeing in community dwelling frail elders, with high level of comorbidity and…
The aim of this pilot-study is to establish the potential efficacy of acute doses of 50 mgs D-cycloserine (DCS), a partial NMDA agonist, in accelerating and/or augmenting the effect of exposure and response prevention (ERP) in the treatment of…
The aim of this study is to evaluate the efficacy of prazosin for the treatment of PTSD related sleep disturbances, and to evaluate response with objective and subjective parameters.
The objective is to investigate wether a brief CBT with parental involvement among children and adolescents with ASD reduces the risk of PTSD compared to a waitlist control group.
The aim of the present study is to establish intero-interoceptive fear conditioning in healthy participants in a differential conditioning paradigm. We want to make use of *real* interoceptive conditioned stimuli: a low respiratory load and small…
1. To investigate the safety and tolerability of single oral doses of NS11821 in healthy male subjects and estimate a maximum tolerated dose.2. To investigate the pharmacokinetics (PK) of single ascending oral doses of NS11821.
An efficiency study will be conducted to evaluate the systematic use of the distress thermometer and its discussion by a nurse as compared to the usual care provided to outpatients who are treated for primary breast cancer by their treating…
In this research study the role of context in extinction will be investigated in healthy adults in a laboratory setting. Renewal of fear will be compared in two contexts of different modality: a visual context (the illumination of the room) and an…
The aim of the present study is to examine whether the positive interpretive training has an therapeutic effect in patients with an anxiety disorder.
The present study is aimed at testing the effects of D-cycloserine in addition to exposure treatment sessions in PTSD patients, in a randomized double blind placebo controlled study.
Exploring whether ABM is more effective than placebo-ABM in changing attentional bias and alleviating PTSD symptoms in patients (from diverse cultural backgrounds) with PTSD.