172 results
Primary Objectives: - Is IBA non-inferior to CBT in treating patients with OCD?Secondary Objectives:-* Does treatment modality predict pre- to posttreatment changes in neural networks, and is this related to symptom reduction and changes in…
The first goal of the current research is to investigate whether EMDR prior to CBT, compared to an active psychological control condition (*supportive counseling*), improves treatment tolerability, adherence, and effectiveness. The second goal is to…
This study has been transitioned to CTIS with ID 2024-514783-78-00 check the CTIS register for the current data. The aim of this project is to investigate CBD as a new medicine to target the ECS in the reduction of anxiety symptoms. Subsidiary aims…
The current project aims to address the three barriers that obstruct children from profiting optimally from CBT. For this purpose, an easy accessible, online, CBT-based training for anxious children (aged 8-13 years) will be developed and assessed…
The main objective is to evaluate the effectiveness of three sessions of EMDR FF (targeting negative FF imagery related to youth*s most feared social situations) in treating social anxiety (lowering anxiety and avoidance related to those feared…
The primary aim of this study is to study the effectiveness of online CT+EMDR (vs. waitlist controls), in terms of reduction in PTSD and depression symptom-levels, for people who have been involved in a traffic accident. We expect that people…
The aim of this experiment is to determine the differential effects of noradrenaline and cortisol on memory accuracy versus generalization and to investigate the divergent effects of these stress mediators on the neural mechanisms underlying the…
The aim is to determine whether individuals with anxiety-related disorders experience faster functional recovery with BI-CBT compared to weekly CBT. If so, a broader range of treatments, decision support, and a detailed implementation plan will be…
Primary Objective: 1. Is FITT more effective than ITT in terms of trauma reduction in children and improvement of structural emotional safety in families? Secondary Objective(s): 1. Is FITT more effective than TAU in terms of trauma reduction in…
The primary objective is to assess the efficacy and cost-effectiveness of 3MDR against conventional TF-PT in the treatment of work-related PTSD. In addition, we will examine whether 3MDR treatment compared to care as usual (CAU) results in a…
The primary goal of the project is to investigate the effectiveness of providing personalized mental health care to patients with OCD, compared to exposure and response prevention (ERP) in the tradi-tional context of a therapist*s room. We will do…
The aim of this project is to investigate the (cost)effectiveness of two innovative forms of trauma-focused therapy for patients with CA-PTSD. The effects will be assessed post-treatment and after a 6 and 12 months follow-up in an intention-to-treat…
Primary Objective: The aim of the proposed study is to investigate whether EMDR is effective in lowering fear of cancer recurrence in patients with familial Melanoma. Secondary Objective(s): effectiveness of EMDR and quality of life at 3 months…
The main objective is to study whether flashforward (FF) EMDR alone is effective in reducing anxiety symptoms in ICD patients.
The primary objective of this study is to evaluate the cost-effectiveness of individual ST (max. 40 sessions) vs. UC in patients with treatment-resistant anxiety disorders from a societal perspective. The second objective is to explore whether…
The primary objective is to study the effectiveness of EMDR in comparison to PE for treating military personnel and veterans with psychological trauma. Secondary objectives are:1. to investigate if working memory capacity is a predictor of EMDR…
The main objective of this study is to evaluate what a newly developed, theory-driven, personalized app, adds to the short- and long-term effectiveness of the existing OST intervention in terms of anxiety symptom reduction and relapse.Three…
To test whether maximizing inhibitory learning can improve exposure efficacy for those suffering from PTSD.
The primary objective of this study is to evaluate the (cost-)effectiveness of ET for late-life anxiety disorders delivered by trained MHNs in primary care, in terms of anxiety and quality of life, compared to UC. UC is not restricted, and the GP is…
The primary aim of the proposed study is to evaluate the effectiveness and cost-effectiveness of a DST for patients with anxiety and/or mood disorders in comparison to UC.The secondary aims are: 1) to identify what works for whom by identifying…