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The effectiveness of Pivotal Response Treatment in children and adolescents with autism spectrum disorder: a randomized clinical trail

Primary Objective: The main objective is to investigate the effectiveness of PRT compared to CAU in school-aged children and adolescents with ASD.The primary research question is:1) Directly after treatment and at follow-up, what is the…

A prospective, double-blind, placebo-controlled trial investigating the efficacy and safety of Org 25935 in relapse prevention in subjects with alcohol dependence

Primary objective- To assess the effects of Org 25935 on heavy drinking in subjects with alcohol dependence.Secondary objectives- assess the effects of Org 25935 on the amount of drinking- To assess the effects of Org 25935 on the first relapse to…

A multisite randomized clinical trial evaluating BP1.3656 vs placebo for alcohol use disorder treatment.

The primary objective of this study is to assess tolerance and efficacy of 12 weeks BP1.3656 (30 µg or 60 µg OD versus placebo) to reduce alcohol consumption in alcohol dependent patients.

Investigating a personalized smoking cessation treatment based on neurocognitive profile: an innovative deep cTBS study

The aim of the study is to investigate whether inhibition of the left or right insula has differential effects with regard to clinical outcomes (i.e. smoking cessation/reduction), cognitive processes (i.e. cognitive control, craving and goal-…