Search for a trial

A randomized, controlled, single-blinded, multicenter clinical trial to evaluate the percutaneous radiofrequency treatment of discogenic pain at the ramus communicans versus a sham-operated group

Investigate the value of percutaneous radiofrequency heat lesion applied to the ramus communicans; more specifically try to determine if a significant and long lasting pain reduction can be obtained as compared to a sham-operated group. In addition…

In search for the optimal treatment for mallet fingers

The evaluate which treatment of mallet fingers is better, the conventional mallet therapy via the hospital or the personalized treatment with intensive follow up via the handencentrum. This will be investigated for mallet fingers caused by an…

The value of Autologous Tenocyte Implantation in patients with chronic Achilles tendinopathy: a double-blind randomised clinical trial

This study is designed to compare the treatment of 2 groups: autologous tenocytes injection in combination with exercises versus saline injection in combination with exercises.

Less pain and more function with physiotherapy treatment of a frozen shoulder? "The cold facts": a randomized controlled trial.

To evaluate the difference in functional outcome, measured by the SPADI, after treatment of adhesive capsulitis with or without physiotherapy

Hydros and Hydros-TA Joint Therapy for Pain Associated with Knee OA;
A Multi-center, Randomized, Double-blind Study to Evaluate the Safety and Efficacy of Hydros and Hydros-TA Joint Therapies for Management of Pain Associated with Osteoarthritis in the Knee

The purpose of this study is to evaluate the safety and efficacy of Hydros-TA Joint Therapy for relief of pain due to OA of the knee. Hydros-TA is designed to provide fast acting and long lasting pain relief for up to six months with a single IA…

Flexible versus standard intramedullary rod in Triathlon primary total knee replacement: effects on sagittal contour of the distal femur, implant positioning, functional outcome and sizing

Primary Objective: To compare the standard IM rod with the flexible IM rod in terms of post-operative sagittal contour of the distal femur. Secondary Objective(s):To compare the standard IM rod with the flexible IM rod in terms of post-operative…

Vitamin D and non-specific musculoskeletal complaints in non-Western immigrants

We aim to assess the effect of high-dose vitamin D supplementation on non-specific musculoskeletal complaints in non-Western vitamin D-deficient immigrants and to determine whether improvement of mood is associated with this effect.

Intraarticular treatment of osteoarthrits of the hip: A randomized trial of hyaluronic acid (Fermathron S) vs corticosteroids (Depomedrol).

Will the hyaluronic acid injections have impact on pain reduction and functional improvement in patients with osteoarthritis of the hip ?

Optimizing the intermanual transfer effects after training with a prosthetic simulator

The objective of this study is to determine the optimal myo-electric prosthesis training for obtaining the largest transfer effect. Here fore we plan to execute three experiments. At first it needs to be revealed which trainingtasks leads to the…

Adrenaline use in local infiltration analgesia during TKA;Randomized, double blind, controlled study

The goal of the pilot study is to compare LIA with or without adrenaline infiltration by means of post operative pain (VAS) scores, PONV, early mobilisation and early discharge criteria.

Intermanual transfer using mental imagery in prosthetic training

The objective of this study is to determine the surplus value of mental imagery on myo-electric prosthesis training Here fore we plan to execute two experiments. The goal of the first experiment is to test if intermanual transfer effects of able-…

Anterior cruciate ligament CT study:
Transtibial, anteromedial portal, tape locking screw reconstruction technique

The main objective of this study is to compare the femur tunnel positioning after AMP, TLS and TT reconstruction techniques. We will also look at the relation between tunnel positioning and tunnel widening.

Second study on the Effect of Teriparatide on Femoral Neck Fracture Healing

Improvement of the functional recovery of patients with a hipfracture and the prevention of re-surgery.

Efficacy of spinal orthosis in nonsurgical treatment of traumatic thoracolumbar fractures

The withhold of the use of a spinal orthosis for traumatic spinal fractures will lead to equal pain, radiologic outcome, and quality of life (QoL) in patients.

Local Infiltration Anaesthesia in Total Hip Arthroplasty by Anterior Supine Intermuscular Approach

Determining the outcome of reversed and antegrade LIA in THA with ASI by analysing postoperative pain with the 100 mm Visual Analogue Scale (NRS), length of hospital stay, the amount of postoperative consumption of opioid pain medication as well as…

Efficacy, Safety, and tolerability of GRT6005 in subjects with moderate to severe chronic low back pain

To assess the analgesic efficacy, safety, and tolerability of once daily orally administered GRT6005 in a total of 3 fixed doses (i.e., 200 µg, 400 µg, and 600 µg GRT6005) compared to placebo in subjects with moderate to severe chronic LBP.

Long term effectiveness of COBRA-light and COBRA treatment in early rheumatoid arthritis

The follow-up study has two main research questions:o Is the treatment of early RA according to the COBRA-light schedule as effective (based on DAS44 score, ACR/EULAR remission criteria, HAQ score and the Sharp/van der Heijde score) as standard…

Joint distraction (KJD) in treatment of knee osteoarthritis: cartilage changes in a comparison with a presently applied surgical alternative: high tibial osteotomy (HTO)

1. To compare cartilage changes after KJD and after HTO, based on MRI, radiographs and biomarkers, evaluated 2 years post treatment. 2. To compare clinical efficacy after KJD and after HTO during 2 year follow-up by a questionnaire (KOOS; for pain,…

Research on the difference in effectiveness between the treatment with plaster versus pressure bandage after hallux valgus correction

The aim of the study is to determine the difference in effectiveness in the treatment of a hallux valgus correction with 2 weeks cast versus pressure bandage treatment with 2 weeks, both followed by 4 weeks with a spica and Post-op shoe.

FlyWheel Training (FWT) study: eccentric overload training on a flywheel ergometer versus standard excentric training for the treatment of patellar tendinopathy in athletes.

The objective of this study is to evaluate if overload eccentric training on a flywheel ergometer, guided by a physiotherapist, is an appropriate training for athletes with patellar tendinopathy to reduce pain and a faster return to sport. The pain…