103 results
To assess the effects on knee pain, function, quality of life and change in structural features with respect to cartilage and subchondral bone of osteotomy surgery after one year of follow-up compared to the effects of treatment with an orthopaedic…
BoneMaster ITo perform a comparative assessment between the clinical, bone remodelling, and radiographic outcomes (as measured with RSA) of the conventional Hydroxyl-Apetite (HA) Taperloc stem compared with Taperloc stem with additional BoneMaster®…
To examine the effectiveness of an unsupervised e-health supported neuromuscular training program in combination with usual care in general practice compared to usual care alone in patients with acute lateral ankle sprains in general practice.
To determine clinical and cost effectiveness and impact on quality of life of surgical intervention (DAIR on day 10) versus nonsurgical treatment in patients with persistent wound leakage.
To investigate whether an add-on mindset & physical therapy program based on the *Wim Hof Method* can safely and efficaciously be applied in patients with active axial spondyloarthritis.
Primary objective: To evaluate the effects of eHealth therapy and usual care in IBD patients with arthralgia and to compare the effects of eHealth interventions plus usual care with just usual care in IBD patients with arthralgia.
The objective is to study the effectiveness of the online self management training Reuma Uitgedaagd! voor adults with a rheumatic disease.
The primary study objective is to determine whether Febuxostat daily 80-120 mg is better than Allopurinol daily 100-600 mg in inducing positive changes in Pulse Wave Velocity (PWV) after 36 weeks of treatment.
Primary Objective: The primary objective of this study is to evaluate the difference in functional outcome, measured by the SPADI, after treatment of a frozen shoulder with or without manipulation under anaesthesia. Primary outcome parameter:…
Primary Objective:What is the effectiveness of immediate opioid pain medication (followed by step-down) versus step-up pain medication within the treatment according general practitioners* clinical guideline in patients with (sub)acute sciatica,…
The primary goal of this non-inferiority study is to show that the Mepilex Border Post op does not perform worse than the Aquacel ® Surgical ® regarding replacing the wounddressing during hospitalization in patients with TKP.In other words; the…
The follow-up study has two main research questions:o Is the treatment of early RA according to the COBRA-light schedule as effective (based on DAS44 score, ACR/EULAR remission criteria, HAQ score and the Sharp/van der Heijde score) as standard…
1. To compare cartilage changes after KJD and after HTO, based on MRI, radiographs and biomarkers, evaluated 2 years post treatment. 2. To compare clinical efficacy after KJD and after HTO during 2 year follow-up by a questionnaire (KOOS; for pain,…
The aim of the study is to determine the difference in effectiveness in the treatment of a hallux valgus correction with 2 weeks cast versus pressure bandage treatment with 2 weeks, both followed by 4 weeks with a spica and Post-op shoe.
To evaluate the clinical impact of the CaFaSpA referral rule in young patients presenting at the general practioners with chronic low back pain, who are at risk for axSpA, compared to usual care.
The main objective of this project is to evaluate the effectiveness and cost-effectiveness of minimal interventional procedures as an add-on to a multidisciplinary pain program for patients with chronic mechanical low back pain who are referred to a…
Determining differences in postoperative swelling of the leg by the use of postoperative compression bandage of the leg versus a control group with no bandage at all, after primary THA by ASI approach. The length of hospital stay and the occurrence…
To research if trapeziectomy with LRTI leads to better results than trapeziectomy on the long term, with subjective and objective outcome measures.
The objective of this study is to examine the 5-year efficacy and safety of Matrix-Induced Autologous Chondrocyte Implantation (MACI® Implant), compared with arthroscopic microfracture, in patients who received study treatment in Genzyme-sponsored…
The present proposal seeks to compare the cardiovascular and gastrointestinal safety and effectiveness of a strategy of initial randomisation to treatment with the selective COX-2 inhibitor celecoxib or to *usual-care* with their current non-…