261 results
To assess the effects and the cost effectiveness of self monitoring of glucose in DM2 patients who are not using insulin on diabetes related distress, glycaemic control and changes in behavioural determinants.
The aim of the Anti-Interleukin-1 in Diabetes Action trial (AIDA) study is to test the feasibility, safety/tolerability and potential efficacy of anti-IL-1 therapy in maintaining or enhancing beta-cell function in people with new-onset Type 1…
The goal of this project is to develop and test a digital file that is expected to improve the communication between professional caregivers (endocrinologists, nurses, dietitians, social workers, psychologists). Additionally, the communication…
Does bilateral deep brain stimulation of the subthalamic nucleus in patients with Parkinson's disease influence plasma triglycerides and glucose metabolism?
The primary objective of this study is to investigate the peri-operative accuracy and safety of the RT-CGMS in cardiac surgical patients.The secondary objective is to identify and define possible factors interfering with reliable and adequate…
The primary aim of this study will be to determine the effect of rosiglitazone on intima media thickness and calcification in patients with stage 4 and 5 CKD. The secondary end points are the effects on pulse wave velocity, blood pressure, the lipid…
The primary objective of this study is to assess the effects on glycaemic control of self adjusting insulin in patients with suboptimal controlled type 2 diabetes starting on insulin, with internet support and strict schedules. In addition, effects…
To study the influence of ingestion of additional leucine on body composition and muscle characteristics in elderly, type 2 diabetes patients.
The primary objective of this study is to evaluate the effects of SYR-322 and SYR-322coadministered with pioglitazone HC1 versus placebo on postprandial triglycerides in subjectswith type 2 diabetes.
1. The primary aim of the study is to investigate whether periodontal treatment results in a decrease of plasma biomarkers that are related to cardiovascular diseases (CVD) and metabolic syndrome (MS) and what is the effect of the treatment on the…
The first objective of this study is to develop a screening program for the Hindustani Surinamese population and to test its feasibility. The second objective is to develop a lifestyle intervention aimed at preventing DM, targeted to the Hindustani…
To study the effect of intensive blood glucose control intraoperatively and 24 hours postoperatively on the occurrence of cardiovascular complications and death from all causes at 30 days and at 1 year after non-cardiac surgery in diabetics.
The main question is: does an ethnic specific cultural approach, including an ethnic specific education programme and individual guidance by a bicultural educator as part of the multidisciplinary team, has a beneficial effect on glycaemic control in…
The primary objective is to compare metformin versus no intervention for incidence of GDM in women with a high risk for GDM. The main secondary objective is pregnancy outcome with Metformin, neonatal outcomes and neonatal complications.
The primary objective of this study is to demonstrate the impact on time in hypoglycaemia (number of hours per day of hypoglycaemic excursions < 3.9 mmol/L, 70 mg/dL) using the Abbott Sensor Based Glucose Monitoring System compared to Self…
The primary objective of EXSCEL will be to evaluate the effect of Bydueron, used in addition to the current usual care for glycemic control, on major macrovascular events when administered to patients with type 2 diabetes.
The purpose of this study is to investigate the effectiveness and safety of dapagliflozin for glucose control in patients with exacerbation COPD on high dose glucocorticoids.Effectiveness of glucose control in clinical practice is measured by the…
Primary objective: What are the long-term effects (i.e. after 8-week drug exposure) of the DPP-4i linagliptin versus the SU derivative glimepiride on fasting and postprandial renal hemodynamics (glomerular filtration rate (GFR)/ effective renal…
To determine the effects of daily administration of hesperidin on glucose/insulin metabolism and intestinal health as assessed by an oral glucose tolerance test (OGTT), and investigation of lipid metabolism, blood pressure, heart rate, gut barrier…
1) To demonstrate the superiority of alirocumab in comparison with placebo in the reduction of calculated low-density lipoproteincholesterol (LDL-C) after 24 weeks of treatment in patients with diabetes treated with insulin and with…