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ENdometrial cancer SURvivors' follow-up carE (ENSURE): Less is more? Randomized controlled trial to evaluate patient satisfaction and cost-effectiveness of a reduced follow-up schedule

The aim of this study is to compare a reduced follow-up schedule of 4 visits among low-risk, early-stage endometrial cancer survivors, with the schedule according to the current Dutch guideline that includes 10 to 13 visits, on:Primary outcomes:1.…

Minimal Invasive versus Non Invasive treatment for symptomatic uterine fibroids: A randomized controlled trial comparing uterine artery embolization with magnetic resonance guided focused ultrasound (MINI TRIAL)

The objective of the MINI-trial is to compare the clinical effectiveness, quality of life, and cost-effectiveness of uterine artery embolisation (UAE) to MR guided focused ultrasound (MRgFUS) in pre- or perimenopausal women with symptomatic uterine…

SIGnificance of routine Hysteroscopy prior to a first 'in vitro fertilization' (IVF) Treatment cycle

The aim of the proposed study is to assess whether diagnosing and treating unsuspected intrauterine abnormalities by saline infusion sonography and/or routine office hysteroscopy prior to a first IVF/ICSI treatment cycle improves the cost-…

Pelvic organ prolapse in general practice: effects of pelvic floor physiotherapy and of pessary treatment

The objective of the project is to study the effect of conservative, non-surgical treatments of pelvic organ prolapse in a randomized clinical trial. The treatments under study, pessaries and pelvic floor physiotherapy, aim at reducing the symptoms…

Multicentered randomized controlled trial to test the cost effectiveness of urodynamics in women with symptoms of stress urinary incontinence in whom surgical treatment is considered.

To test the value of preoperatively performed urodynamics with regard to outcome of surgery for stress urinary incontinence (SUI) and to examine whether not performing urodynamics preoperatively is more cost effective than performing urodynamics…

One day versus three day suprapubic catheterisation after vaginal prolapse surgery: a randomized controlled trial.

To determine the optimal moment to start bladder training after vaginal prolapse surgery with anterior colporrhaphy.

VAginal NOTES versus Laparoscopic hysterectomy in Uterine Endometrioid Cancer (VALUE-study): a multicentre randomized trial.

To evaluate the duration of admission, feasibility, patient satisfaction and complication rate of vNOTES hysterectomy with BSO and compare it with laparoscopic hysterectomy with BSO in case of clinical stage 1 low grade endometrial cancer.

At-home yoga for endometriosis-related pain.

What is the effectiveness of at-home yoga-intervention for women suffering from pain due to endometriosis when compared to no yoga intervention.

MYCHOICE: The MYoma treatment Comparison study: High intensity image guided fOcused ultrasound versus standard (minimally) Invasive fibroid care - a (Cost) Effectiveness analysis

To determine the long-term (cost)effectiveness of Magnetic Resonance image guided High Intensity Focused Ultrasound (MR-HIFU) compared to standard (minimally) invasive fibroid care in-cluding UAE, myomectomy and hysterectomy.

A Phase 2, Randomized Study of MLN0128 (a Dual TORC1/2 Inhibitor), MLN0128+MLN1117 (a PI3Kα Inhibitor), Weekly Paclitaxel, or the Combination of Weekly Paclitaxel and MLN0128 in Women With Advanced, Recurrent, or Persistent Endometrial Cancer

The primary objective of this phase 2 study in patients with advanced endometrial cancer is to compare the clinical efficacy of MLN0128 + weekly paclitaxel to weekly paclitaxel alone in second- or third-line treatment of advanced, recurrent, or…

Study on shared decision making in choosing a treatment for pelvic organ prolapse

The use of an interactive web-based Decision Aid reduces decisional conflict and increases patient satisfaction with information and care.