82 results
Primary objective is to investigate whether a VF-based balance training program leads to improved balance control in PD patients and how posturographic outcomes are associated with changes in clinical outcome measures.Secondary objective is to…
1) To evaluate the efficacy of knee-ankle-foot orthoses (worn by night) in preventing a decrease of range of motion to ankle dorsiflexion in children with cerebral palsy (Clinical part). 2) To evaluate the effect of night-worn knee-ankle-foot…
The present PhD thesis focuses on the investigation of ADAS and the older driver. Even though, recent research investigated the effects of ADAS on driving performance, little is known about the long-term effects of the systems on performance.…
- to examine the safety and tolerability of the research medication- to examine how the research medication is absorbed, broken down and excreted by the body.
Primary• To assess the efficacy of a fixed dose of pregabalin to placebo during the first12-week treatment period in subjects with RLS.• To compare the rate of augmentation of a fixed dose of pregabalin to 2 fixed doses ofpramipexole over 9 or 12…
Hypotheses:1. RTX to the salivary glands is a safe and effective treatment of sialorrhoea; 2. RTX to the submandibular glands is at least as effective as RTX to parotid glands 3. RTX to submandibular glands causes less adverse events than RTX to…
This pilot study comprises two objectives.The size of this phase III trial and the choice for a specific primary outcome will depend on the sensitivity of the outcomes to differences, the design of the study and the statistical properties of the…
To demonstrate the extent to which an intervention that combines treadmill training augmented by virtual reality (TT+VR) reduces fall risk, improves mobility and enhances cognitive function in a diverse group of older adults, compared to a treadmill…
This is a placebo- and active-controlled dose-range-finding study which isalso designed to assess the efficacy and safety of preladenant 2, 5, 10 mg twicedaily versus placebo as an adjunct therapy to L-dopa when administered to subjectswith moderate…
The primary objective is to study the effects of 12 weeks of treadmill training with virtual reality on neural plasticity in comparison to the effects of treadmill training without virtual reality.Secondary objectives are to investigate the role of…
This project is motivated by neuroscientific theory regarding the role of the mesolimbic dopamine system in selective attention. It aims to elucidate how the dopamine system affects attention and to determine the role abnormal functioning of this…
The purpose of this study is to determine the effects of a strength training program on physical functioning in children with CP.
To investigate cerebral activation patterns after administration of an AChE-I (rivastigmine), compared to activation after placebo, in PD patients with VH.Secondly, to investigate whether cerebral activation changes after rivastigmine correlates…
To investigate whether impairments of shifting between response sets underlie motor freezing in PD and to investigate the efficacy and the neural mechanism by which MPH improves gait and cognition in PD patients with FOG.
To evaluate the effect of treatment with BoNT on psychogenic jerks.
The primary objective is to evaluate the effectiveness of occupational therapy in improving daily functioning of patients with Parkinson's Disease and reducing caregivers* burden.
The overall aim of the proposed research project is to investigate the therapeutic potential of mental practice embedded in daily therapy on the improvement in daily activities of adult patients with Parkinson*s disease and stroke patients. In the…
Does bilateral deep brain stimulation of the subthalamic nucleus in patients with Parkinson's disease influence plasma triglycerides and glucose metabolism?
The primary goal of this study is to understand the sentence comprehension difficulties in Dutch speaking PD patients. Secondly, we developed the two experiments to test the hypothesis that the BG are involved and play a particular role in syntactic…
First aim of the study is to investigate whether a physical activity promotion program will result in a improvement in physical activity in sedentary patients with PD. Furthermore, the related health benefits will be analysed.