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Transcendental Meditation or Hypnotherapy versus Standard Medical Care for the Treatment of Children with Primary Headaches: a Multi-Centre, Pragmatic, Randomized Clinical Study

The goal of this pragmatic, randomized controlled study is to determine the effectiveness of two relaxation techniques, eg. TM or HT added to the treatment of paediatric primary headaches in comparison to standard medical treatment (SMT). TM or HT…

The efficacy of internet training for migraine self-management

Primary ObjectivesThe primary objectives of this study are to establish:1. The efficacy of internet-delivered SMT for chronic migraine - compared to waitlist control- regarding the post-training improvement of migraine attacks and headache days per…

The feasibility, desirability and effects of physical activity coaching and feedback on the level of physical activity of patients with migraine - a pilot study

Primary objective is firstly to test the feasibility and the desirability of an intervention including coaching sessions and a pedometer both to improve the level of physical activity of patients with migraine, secondly to explore the difference in…

Open-label randomized controlled trial for the effects of continuous ethinylestradiol/levonorgestrel (30/150 µg/day) compared with vitamin E (400 IU/day) in the treatment of menstrually-related migraine and migraine during perimenopause

This study has been transitioned to CTIS with ID 2024-517127-40-00 check the CTIS register for the current data. To study the effects of continuous use of ethinylestradiol/levonorgestrel (30/150 µg/day) compared to vitamin E (400 IU/day) in the…

A 12-month prospective, randomized, interventional, global, multi-center, active-controlled study comparing sustained benefit of two treatment paradigms (erenumab qm vs. oral prophylactics) in adult episodic migraine patients

The purpose of this study is to determine the sustained benefit on safety and efficacy of AMG 334 compared to oral prophylactics in episodic migraine patients who have previously failed 1 to 2 prophylactic migraine treatments and therefore have a…