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Step-down versus step-up analgesics in patients with (sub)acute sciatica in primary care

Primary Objective:What is the effectiveness of immediate opioid pain medication (followed by step-down) versus step-up pain medication within the treatment according general practitioners* clinical guideline in patients with (sub)acute sciatica,…

Neurogenic bladder in children: use of feed-back tools during standard treatment with anticholinergics.

We aim to increase patient compliance by extending the existing treatment protocol of (oral or intravesical) anticholinergics plus application of CIC with the addition of bladder pressure measurement performed at home during CIC plus access to an…

(Cost) Effectiveness of Surgery versus Prolonged Conservative Treatment in Patients with Intermittent Neurogenic Claudication caused by Lumbar Stenosis

Intermittent neurogenic claudication due to lumbar stenosis is frequently diagnosed among older persons. Due to an aging population it is to be expected the incidence of lumbar stenosis will increase over time. Patients are operated on because of…

The effects of hybrid cycle exercise training in inactive people with a chronic spinal cord injury.

The primary objective is to evaluate the short- and long-term effectiveness of a hybrid cycle training program on physical capacity, active lifestyle, participation, and quality of life among a group of inactive individuals with a chronic SCI.…

The effect of 16-week low-intensity wheelchair training on functions, activities, and participation in inactive people with a spinal cord injury.

The primary objective is to evaluate the effectiveness of low-intensity hand rim wheelchair exercise training on physical capacity, daily (wheelchair) functioning, participation and quality of life in people with a spinal cord injury. Furthermore,…

Cervical spine movement, before and after anterior cervical discectomy (ACD).
ACD, pure intervertebral discectomy (1) compared to intervertebral discectomy followed by implantation of an intervertebral disc prosthesis (2) in patients with a radicular syndrome. A randomised study

Objective of the study is to verify whether the movement pattern after anterior cervical discectomy normalises, in case of implantation of a cervical disc prosthesis.

Cost-effectiveness of nerve root decompression according to Gill versus instrumented fusion in the treatment of spondylolytic spondylolisthesis; a multicenter prospective randomised trial.

The Sciatica-Gill trial is a randomised cost-effective study about nerve root decompression according to Gill versus instrumented fusion in the treatment of patients with radicular legpain or neurogenic claudication due to spondylolytic…

Epidural compared to General Anesthesia for Lumbar Spine Surgery

To assess whether there is less peri-operative pain and a faster post operative recovery.

Multidisciplinary behavioural program for coping with chronic neuropathic pain following spinal cord injury.

To evaluate a group treatment program to stimulate effective coping with chronic neuropathic pain following spinal cord injury.

The CHARACTER SCS Study: A randomised pilot study to assess differenCes in tHe subjects* experience of stimulAtion-Induced paRaesthesiA between two different spinal Cord sTimulation dEvices: the Axium® DoRsal Root Ganglion Stimulation System Versus the Prime Advanced* Dorsal Column Stimulation System

The principal goal of this study is to compare subjects* experience of Spinal Cord Stimulation (SCS) with two different types of SCS device.

Cost-effectiveness of minimal invasive spinal fusion compared to open fusion for patients with spinal stenosis with neurogenic claudication or radicular leg pain.

What is the cost-effectiveness of minimal invasive posterior lumbar interbody fusion in spinal stenosis patients, compared to the standard open fusion?

Effect of GRAIL training in incomplete spinal cord injury

Both interventions (GRAIL training & endurance and strength training (control intervention)) will result in an increase in gait speed, functional walking ability and social participation. However, the GRAIL training will result in larger…

Surgical Thoracic Outlet decompression versus conservative approach for Patients with Neurogenic Thoracic Outlet Syndrome, a randomized controlled trial (STOPNTOS)

The objective of this study is to determine the value of TOD (first rib resection with partial scalenectomy and neurolysis) on functionality and quality of life. We will do this by randomizing patients into who already received physiotherapy into…

WHeelchair ExercisE and Lifestyle Study

To systematically develop a mobile lifestyle application + counseling program for wheelchair users with a spinal cord injury or lower limb amputation. The intended application is aimed at promoting physical activity, healthy eating habits and…

The use of direct nerve visualisation with the Evotouch/7starscope compared to the conventional fluoroscopy technique for transforaminal epidural injection.

We hypothesize that using the Evotouch/7stascope, ultrasound guided TFEI procedures are non-inferior to the golden standard with fluoroscopy, which means correct placement of the needle within the neuroforamen without intravascular positioning.

Efficacy of the Myosuit for increasing daily life gait performance in the home and community setting and gait capacity in people with incomplete spinal cord injury

Part A:The primary objective is to test the efficacy of the Myosuit, a soft exosuit, for increasing daily life gait performance in the home and community setting in people with iSCI. Secondary, the efficacy of the Myosuit program on gait capacity…

Minimally Invasive Surgery versus Open Surgery (MISOS) in the treatment of spondylolisthesis; a randomised controlled trial.

To document whether patients treated with minimally invasive surgery experience less back pain at 2 and 6 weeks after surgery, compared to patients treated with conventional open instrumented surgery.

The effect of GRAIL training on functional walking capacity and social participation in patients with incomplete spinal cord injury.

The main objective of this study was to evaluate the effect of 6 weeks of GRAIL training on functional walking capacity compared to endurance and strength training (control intervention) in ambulatory patients with chronic iSCI. In addition the…

The effectiveness of the Wim Hof Method on the physical and mental health of people with a spinal cord injury

The primary objective of this trial is to assess the effects of WHM, involving breathing exercises, mindset (and cold exposure), on health-related quality of life in people with SCI. The secondary objectives are to assess the effects of WHM,…

Comparison of DTM SCS Therapy Combined with standard pain treatment to standard pain treatment alone in the Treatment of Intractable Back Pain Subjects without previous history of Lumbar Spine Surgery

The purpose of this study is to evaluate and document the safety information, how effective and cost effective the DTM SCS stimulation system is and the standard pain treatment in patients with chronic, difficult to treat back pain who are not…