1577 results
The primary objective is to assess feasibility of a food supplement (multispecies probiotic) placebo-controlled, randomised controlled, double blind intervention in pregnant women in their late second/third trimester of pregnancy, to reduce symptoms…
The primary objective is to investigate and compare the pharmacokinetic (PK) of MSB11022 acetate versus MSB11022-citrate in healthy subjects.
To investigate the effects of in-phase and anti-phase bilateral frontal theta tACS (5 Hz) on gambling behaviour and endogenous frontal theta activity.
Comparing the additional effects of UVB irradiation to oral vitamin D supplementation on well-being and quality of life in psycho-geriatric nursing home residents.
The primary objective of this study is:After 3 treatment cycles in healthy female subjects between the ages of 18 and 50 years (inclusive): To estimate the effect of the ENG-E2 vaginal ring compared with the LNG-EE COC on hemostatic parameters that…
The aim of the present study is to determine the effect of vaccination on anti-oxLDL antibodies in man.
To determine the mechanisms underlying motor skill training, somatosensory electrical stimulation, and a combined intervention on motor skill acquisition, motor memory consolidation, and interlimb transfer in healthy younger and older adults.
The main aim of this phase-II-proof-of-principle study is to test whether the health game AquaSnap offers improvement of cognitive impairment in PD patients with mild cognitive impairment, using an RCT. The long-term ambition is to test whether the…
Part I:To assess the efficacy of two doses of MK-8931 on cognition in subjects with mild to moderate AD.To assess the efficacy of two doses of MK-8931 on functional ability in activities of daily living in subjects with mild to moderate AD.To assess…
To investigate whether bright light therapy is an effective treatment for depression during pregnancy compared with low-intensity placebo light therapy (proof-of-principle) and to investigate the late effects of bright light therapy versus placebo…
The current study investigates whether the ASPI-score is sensitive to context in which the ASPI is administered. Because the ASPI was designed to measure the capacity to experience sexual pleasure, it is expected that the ASPI score will not vary…
In this trial we now aim to investigate comprehensively the effect of riboflavin supplementation on the abundance of F. prausnitzii and on other members of the gut microbiota in faeces of healthy volunteers. Additionally we will assess whether…
The main objective is to improve predictability of orthognatic surgery, or in other words to realise a stronger relation between (3D virtual) pre-operative planning and post-operative result. The second objective is to evaluate the surgeon*s…
The objectives of the study are to assess whether:(1) SNP will reduce the occurrence of psychomimetic side effects during exposure to low-dose ketamine;(2) SNP will reduce the ketamine-induced increase in blood pressure and cardiac output;(3) SNP is…
The aim of this study is to evaluate if direct removal of the urine catheter after an LH (total laparoscopic hysterectomy and laparoscopic supracervical hysterectomy) is associated with similar (or better) outcomes compared to catheter removal the…
Primary Objective: Assessment of a group difference in clinically important improvement in functional outcome of at least 10 points as measured by the DASH questionnaireSecondary Objective(s): 1. To determine if there is a group difference in…
To investigate whether an adjunctive YBSR program added to standard care compared to standard care alone, can reduce:1.fatigue symptoms (primary objective)2.psychological distressand improve:3.health-related quality of life4.sense of coherence5.…
The purpose of the present study is to investigate the effects of light therapy (with two different light boxes) on depression in people with intellectual disability (IQ *70 ) compared to standard care (care as usual).
This study aims at investigating the efficacy of two home-based interventions, an ambulant personalized acitivity feedback intervention (AAF) and an online mindfulness-based cognitive therapy (MBCT) in reducing chronic cancer-related fatigue…
To evaluate the efficacy of NEOD001 plus standard of care vs. placebo plus standard of care when administered intravenously in subjects with AL amyloidosis by assessing time to all-cause mortality or cardiac hospitalizationSecondary ObjectivesIn…