161 results
Objectives of this study are to determine whether Vicryl rapide ® or Monocryl ® is the optimal suture material for closing the skin in the suturing of an episiotomy. This will be done by determining pain and dyspareunia at several intervals after…
To assess in women with a request for pain relief during labour the cost-effectiveness of remifentanil patient controlled analgesia (RPCA) as first choice compared to EA.
In view of the outcome of the HYPITAT study, one can raise the question how women with preeclampsia or severe hypertension between 34 and 37 weeks of gestation should be managed. Induction of labour might prevent maternal complications. However,…
In the present proposal, we aim to answer whether antenatal allopurinol administration does reduce hypoxic-ischaemic encephalopathy in neonates exposed to intra-uterine asphyxia.
The project aims to gain more insight in the process of bonding between parents and prenature infants, to validate a screening instrument that can be easily adopted in maternity wards of (general) hospitals to detect parents and children at risk for…
To optimize the quality and cost-effectiveness of care for jaundiced neonates in the Isala Klinieken.
This study will answer the question whether surgical intervention (metroplasty) in women with recurrent miscarriage and/or subfertility and a septate uterus will improve their reproductive outcome.
The objective of this study is to gain insights into the value of the proposition *Origo* for women and their loved ones, medical staff and care institution.
Primary objective: To evaluate the efficiency of the daycare treatment of pregnant women with a psychiatric disorder.Secondary objective:Differs groupwise daycare treatment in efficiency towards standard individual outpatient care, in terms of:a.…
The objective of this study is to determine whether retention of cerclage after PPROM improves latency (without a significant increase in chorioamnionitis) and lessens neonatal morbidity.
The primary aim of this study is to determine to what extent FBS is effective in preventing unnecessary operative delivery for CTG-suspected fetal distress. The secondary aims are to determine if FBS does not enhance poor perinatal outcome. Tertiary…
In the proposed study, two main issues will be addressed: first, it will be studied whether a high dose (4.0 mg) of FA supplementation periconceptional has an added value over the now recommended low dose of 0.4 mg in the prevention of congenital…
SIGnificance of routine Hysteroscopy prior to a first 'in vitro fertilization' (IVF) Treatment cycle
The aim of the proposed study is to assess whether diagnosing and treating unsuspected intrauterine abnormalities by saline infusion sonography and/or routine office hysteroscopy prior to a first IVF/ICSI treatment cycle improves the cost-…
The main objective is to study the effect of vitamin D supplementation on insulin sensitivity in patients with gestational diabetes mellitus.
Primary objective: To assess in term pregnant women with an unfavourable cervix (Bishop score < 6, Appendix1) the time interval between induction of labour and birth with a transcervical Foley catheter filled with 30mL compared to induction…
To compare neonatal mortality and short-term (advanced MRI indices of structural brain injury at 40 weeks* GA) and long-term neurodevelopmental outcomes (Bayley scales of infant development III [BSID-III] at 24 months) between two groups of very…
To compare which treatment (indwelling catheter versus intermittend catheterisation) has the best clinical effect in women with symptomatic PUR.
To judge if there is a difference between referral rates during labour when an amniotomy is performed in the latent phase of labour, compared to an expectant policy.
Assess whether InsuVital intake improves the postprandial glucose, insulin and C-peptide response
The objective of this study is to find out is the way contractions are maesurent during labor are of any influence on the lenght and the way women deliver. It also looks if there is any influence on neonatal outcome.