20 results
The APOSTEL-VI study will assess whether a cervical pessary prolongs pregnancy in women who have been admitted for threatened preterm labor with a positive fibronectin test, but remained undelivered. Furthermore we will study whether a cervical…
To assess whether a higher prophylactic platelet transfusion threshold is superior to the lower thresholds in reducing the proportion of patients who experience a major bleed or death up to study day 28.
The primary objective of the SafeBoosC trial is to examine if it is possible to stabilise the cerebral oxygenation of extremely preterm infants (gestational age < 28 wks) during the first 72 hours of life through the application of cerebral…
The primary objective of this study is to compare the level of stress and comfort of preterm infants when sedation is given during the MIST procedure compared to no sedation.
In the present proposal, we aim to answer whether antenatal allopurinol administration does reduce hypoxic-ischaemic encephalopathy in neonates exposed to intra-uterine asphyxia.
Investigate the effect of acidic and neutral oligosaccharides supplemented enteral nutrition on infectious morbidity, feeding tolerance and short-term outcome in VLBW infants. Furthermore, an attempt is made to elucidate the role of acidic and…
1. To prevent multiple pregnancies and the concomittant neonatal mortality and morbidity while retaining acceptable delivery rates in couples with unexplained subfertility or mild male subfertility and poor fertility prospects. 2. To assess the…
AimTo determine whether the prophylactic use of IVIg reduces the need for ET in neonates with Rh-D hemolytic disease.
The objective of this study is to compare the direct effect of repetitive tactile stimulation versus standard stimulation on the respiratory effort of preterm infants during stabilisation at birth. The most ideal comparison would be to compare…
To compare the effectiveness of progesterone and cervical pessary in the prevention of preterm birth in women with singleton and twin pregnancies and a short cervix.
The primary objective of this study is to investigate whether darbepoetin alfa is effective in reducing the incidence of late anemia in infants with HDN treated with IUT and therefore in decreasing the number of top-up transfusion required per…
To compare the effect of a HCPAP with LCPAP on oxygenation in the first 5 minutes during stabilization in preterm infants at birth.
To compare the effect of umbilical cord clamping after cardiopulmonary stabilisation (Physiological Based Cord Clamping; PBCC) to standard care (Time Based Cord Clamping; TBCC) on intact survival and health care costs in preterm infants.
This study has been transitioned to CTIS with ID 2024-513042-12-01 check the CTIS register for the current data. To perform a double-blind randomized placebo controlled multicenter study with darbepoetin in infants with MRI confirmed PAIS and to…
This study will evaluate if neonatal effects as described in previous studies are seen in delayed umbilical cord clamping in caesarean sections. Moreover, we will review the maternal effects compared to conventional cord milking in caesarean…
Primary Objective: To evaluate whether PBCC results in a reduced incidence of pulmonary hypertension in infants with CDH 24hrs after birth.Secondary Objectives: To measure and monitor physiological parameters during transition to provide information…
To assess the effectiveness of low dose aspirin compared with placebo in prevention of recurrent spontaneous preterm birth.
To evaluate whether cervical pessary can replace cervical cerclage in women with previous preterm birth and a short cervix or in women with a history of multiple preterm births in terms of effectiveness and costs
The objective of this study is to compare the direct effect of the administration of an initial FiO2 of 1.0 versus 0.3 on respiratory effort during stabilisation of preterm infants in the first 5 minutes after birth. After evaluation of the initial…
To test whether stabilisation of preterm infants with PBCC using the Concord is at least as effective when compared to the standard approach using the standard resuscitation table.