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Implementing Treatment Algorithms for the Cure of Trauma Induced Coagulopathy (iTACTIC)

The primary objective is to compare the haemostatic effect of VHA-guided transfusion strategy versus optimized CCT guided transfusion strategy in haemorrhaging trauma patients. The secondary objectives of the study are to determine the effects of…

Development of chronic disease in newly diagnosed Idiopathic Thrombocytopenic Purpura of Childhood. A randomized controlled study on the influence of treatment with intravenous gammaglobulin on the course of the disease.

To test the hypothesis that IVIG treatment diminish the risk of development of chronic disease, we designed a prospective clinical intervention study in children with newly diagnosed ITP.

Rosuvastatin use to improve the coagulation profile in patients with venous thrombosis: The STAtins Reduce Thrombophilia (START) Study

To understand why statins are able to decrease the risk of developing venous thrombosis, by analyzing whether statins can influence pathways that inhibit coagulation.

Sodium Bicarbonate for the prevention of contrast induced nephropathy in patients suspected with acute pulmonary embolism undergoing CTPA

- Evaluation of mean increase in serum creatinine and the incidence of CIN following CT-PA without prehydration compaired to a short prehydration regime with sodium bicarbonate during one hour.- Furthermore, the risk of developing CIN after CT-PA…

Sodium Bicarbonate versus Saline for the prevention of Contrast Induced Nephropathy in patients undergoing CT-angiography.

• Evaluation of the incidence of CIN after CT-angiography with a hydration regime during 1 hour with sodium bicarbonate compaired to a hydration regime with saline during 24 hours.• Furthermore the risk for developing CIN after CT-angiography is…

RCT comparing the levonorgestrel releasing intrauterine system (Mirena) versus endometrial ablation in women suffering from menorrhagia

We plan to compare the costs and effects of both methods.