187 results
In patients diagnosed with a hip fracture who also have acute myocardial injury on presentation to hospital, is accelerated surgery superior to standard care for the primary outcome of death at 90 days after randomization?
To demonstrate that removal of drains exclusively based on digital drainage system data is non-inferior to additional clamping trials regarding recurrent pneumothorax requiring chest tube reinsertion.
Assess amyloid beta clearance from CSF to serum in response to HFCWO in healthy volunteers:- Change from baseline in amyloid beta 40 (ng/ml) in CSFAssess endogenous protein biomarker clearance from CSF to serum in response to HFCWO in healthy…
The main objective is to determine function/clinical outcome, measured by the NRS-11 score for pain, 3 months after intervention and compare this between the surgery and conservative group. Secondary objectives are functional outcome as measured by…
The primary objective is to demonstrate efficacy of an extended remote monitoring intervention, including a TM app, HF nurse guided home care and multidisciplinary network collaboration using the Virtual Ward platform, on top of standard HF care…
To evaluate in SSc patients with low risk for disease progression 1) whether assessment in an outpatient clinic setting is an acceptable alternative for evaluation in the Care Pathway. Outcome parameters we will evaluate include 1) health care…
To assess the impact of SABR, compared to standard of care treatment, on overall survival, oncologic outcomes, and quality of life in patients with a controlled primary tumor and 4-10 metastatic lesions.
The primary objective of this study is to examine whether MIS is non-inferior to laparotomy in terms of disease free survival (DFS) in women with advanced stage EOC that received 3 to 4 cycles of NACT.
The purpose of this study is to determine the effect of using the Happi Liver application on the course of the liver disease non-alcoholic fatty liver disease (NAFLD).
To establish the safety and effectiveness of the Edwards SAPIEN 3/ SAPIEN 3 Ultra Transcatheter Heart Valve (THV) in subjects with moderate, calcific aortic stenosis (AS)
The aim is to evaluate whether the use of eRFA prior to stenting prolongs stent patency in patients with biliary obstruction due to inoperable perihilar cholangocarcinoma.
Does isolated cup revision surgery or liner exchange through the anterior approach result in increased functional status and higher patient satisfaction than through the posterolateral approach?
To assess the impact of SBRT in combination with systemic therapy compared to systemic therapy alone on safety and efficacy in patients with mCRC.
This study has been transitioned to CTIS with ID 2023-505483-11-00 check the CTIS register for the current data. To investigate if early transition to oral treatment after two weeks or longer of IV antibiotic therapy is non-inferior to standard six…
This study will evaluate the effectiveness and safety of a 36-week refill regimen for the PDS with ranibizumab 100 mg/mL (PDS Q36W) compared with intravitreal injections of aflibercept (2 mg) administered per a treat-and-extend regimen (aflibercept…
The primary objective of this study is to evaluate the feasibility of MI-E in invasively ventilated critically ill patients. The secondary objective is to evaluate safety and explore data on the efficacy of MI-E in invasively ventilated critically…
The aim of the current project is to test the clinical and cost-effectiveness of GST for patients with an ED (i.e., anorexia nervosa, bulimia nervosa, other specified), that are not likely to benefit from CBT-E. The study will focus on those…
The study aims to determine the effectiveness of the application of AET in decreasing self-reported deficits in autonomy-connectedness / self-reported symptoms of anxiety and depression in HI adults.
Comparing different ventilation strategies in focal and non-focal ARDS in invasively ventilated patients admitted to the intensive care unit.
We hypothesize that using the Evotouch/7stascope, ultrasound guided TFEI procedures are non-inferior to the golden standard with fluoroscopy, which means correct placement of the needle within the neuroforamen without intravascular positioning.