78 results
2. OBJECTIVESThe overarching goal of this proposal is to examine the feasibility and effectiveness of mobile-based screening for MDD. We combine validated screening and interventions for MDD with innovative outreach methods to maximize impact.…
To determine whether guided growth of the proximal femur decreases the risk of further hip migration and need for further surgery in cerebral palsy patients.
Demonstrate that the self-expandable Allegra TAVI system provides lower mean gradient assessed by TTE compared to balloon-expandable valve systems in a population of all women patients with symptomatic severe aortic valve stenosis.
In the current study, the subjective and objective effectiveness of cognitive rehabilitation therapy for people with somatic symptom and related disorders will be investigated. Additionally, the effects of this treatment on brain activity in the…
The aim of this study is to compare the effect of twice daily MI-E to twice daily AS with MAC on increase of PECF in patients with SMA with weak cough over a period of 3 years.
Primary: To assess the effects of a 2-week preoperative vegan diet in comparison to an omnivorous diet on protein synthesis rates in Hoffa*s fat pad, synovium, bone, ligaments, menisci, and cartilage in older adults with knee osteoarthritis…
Objective: To test if participants with autism engaging in a CBT-I based online guided intervention (i-Sleep Autism) will experience a significant reduction in insomnia symptoms and improved mental health outcomes compared to the control group (…
To improve survival and qualitity of life in patients with LAPC using ablative treatment with MRgRT (5x10Gy) in addition to standard of care.
Does mindfulness based cognitive therapy in addition to treatment as usual (TAU) improve QoL compared to TAU alone in patients with CPP based on a hypertonic pelvic floor ?
The objective of this study is to prospectively compare decongestive therapy administered by the Reprieve DMS system to Optimal Diuretic Therapy (ODT) in the treatment of patients diagnosed with acute decompensated heart failure (ADHF). The main…
To investigate the impact of BT as compared to standard of care in severe asthma patients that remain uncontrolled despite standard treatment including adequate doses of inhaled preventer therapies with or without biologics on:(1) rate of…
The main objective of this study is to establish the efficacy of *pit picking with laser therapy* versus *pit picking alone* on both short and long-term outcomes.
1. At 1 year, to demonstrate non-inferiority for target vessel failure (TVF) of a treatment strategy with first line SELUTION SLR* DEB + provisional DES vs. systematic treatment with DES for the treatment of de novo coronary lesions.2. At 5-year…
Evidence showing which aftertreatment protocol is best for both fracture healing and functional outcomes for patients with Displaced Intra-Articular Calcaneal Fractures (DIACFs) is lacking. This study has the aim to answer the question whether…
To evaluate and compare the survival outcome of patients with first recurrence of glioblastoma undergoing surgical debulking/resection followed by either implantation of the SC9 device and repeat BBB opening in association with carboplatin…
Primary intervention objective: to evaluate change in emotion dysregulation in at-risk-for-ADHD toddlers (24-36 months) during the 8-week intervention period of MASTER compared to the 6-week baseline (control) period. Secondary intervention…
The first objective is to test whether the tool is promising for individuals to support them in managing their problematic use of CSAM. The second objective is to develop a blueprint to maximize the reach and impact of safety technology for…
To assess non-inferiority of treating patients with localized, intermediate risk prostate cancer in two fractions of 12 Gray (Gy) with a boost to the gross tumor volume of 13.5 Gy per fraction in 8 days, as compared to standard care (36.25 Gy in…
Primary objective: determine whether HAPTOS intervention results in earlier attainment (postnatal days) of full enteral feeding and/or full oral feeding (postmenstrual age) compared to standard care. Secondary objectives: To determine whether Haptos…
Primary Objective The primary objective of this study is to compare the 3-year overall survival of stage III NSCLC patients during follow-up surveillance with 18F FDG PET/CT versus follow-up with conventional CT surveillance. Secondary Objectives…