342 results
To evaluate the effectiveness of eccentric calf muscle exercise therapy compared to strength training of the upper extremities (control group) in patients with chronic midportion Achilles tendinopathy.
Both interventions (GRAIL training & endurance and strength training (control intervention)) will result in an increase in gait speed, functional walking ability and social participation. However, the GRAIL training will result in larger…
This multicentre randomised controlled trial aims to investigate whether PoCUS can be used as an adjunct to improve first attempt success rate in closed reductions of displaced distal radial fractures in adults in the ED.
To investigate if patient controlled sublingual sufentanil tablets as compared to patient controlled intravenous morphine lead to improved independent mobilization on postoperative day 1 after laparoscopic donor nephrectomy (LDN).
To investigate if a personalized dietary advice is more effective in increasing dietary fiber intake in the Dutch population than the general advice that is currently provided by the Netherlands Nutrition center and the Dutch Digestive Foundation (…
To evaluate the effectiveness of eccentric calf muscle exercise therapy compared to strength training of the upper extremities (control group) in patients with chronic midportion Achilles tendinopathy.
Relevancy: Groin explorations are regularly performed procedures in vascular surgery. To date, the chosen technique will be either electrocoagulation or the Ligasure, depending on the operator*s preference. It is yet unclear whether the chosen…
The primary objective of this study is to compare the changes in neuromuscular control related to reactive and adaptive movements during balance and gait, following Dynamic C-mill Training to conventional physiotherapy. Furthermore, an additional…
To quantify clinical and histological changes of the skin in promoting early wound healing when SVF + PRP injectable is used as treatment in comparison to SVF and PRP alone.
The purpose of our study is to test the effect of a computer-based cognitive behavioral intervention (called Cognitive Bias Modification, CBM) on affective symptoms in oncology patients. Here we are collaborating with the Oncology department of the…
Objective: The primary objective is to examine whether EMDR therapy has mood-stabilizing effects in traumatized patients with mild depressive and/or manic symptoms. The secondary objective is to examine the hypothesis that EMDR is an effective and…
To explore the effect of a nutrition and lifestyle intervention on quality of life for patients suffering from PuLmonary Arterial Hypertension.
Primary objective:Is guided online treatment, based on CGT with mindfull- and exposure exercises, with minimal patient contact, effective for IBS-patients as compared to a waiting list?Secondary objectives: Will the guided online treatment lead to…
The major aim of the proposed project is to investigate the clinical relevance of early identification and adequate treatment of co-occurring sleep disorders in people suffering from mental disorders. The main questions underlying the present…
The main objective of this study is to determine whether supplementation with FO combined with complex phospholipids can alter skeletal muscle mitochondrial function more effectively than FO alone. Additional exploratory objectives are;…
The aim is to demonstrate the effectiveness of personalized and home-based speech therapy on quality of life, intelligibility and social participation for people with Parkinson*s disease who have a reduced intelligibility of speech.
The purpose of this study is to investigate the efficacy, safety, durability, and pharmacokinetics of faricimab administered at up to 16-week intervals to treatment-naive patients with nAMD.
Objectives:Primary objective:To evaluate the efficacy of the 3 selected dose regimens of Padsevonil (PSL) administered concomitantly with up to 3 antiepileptic drugs (AEDs) compared with Placebo for treatment of observable focal-onset seizures in…
Primary objective: To evaluate effectiveness, directly after intervention, of an individual face to face Managing Fatigue program on participation for people with NMD, including FSHD or MM compared to a control group receiving usual care.Secondary…
Primary objectives: 1. To compare the efficacy of vamorolone administered orally at daily doses of 6.0 mg/kg over a 24-week treatment period vs. placebo in ambulant boys ages 4 to <7 years with DMD; and2. To evaluate the safety and…