15 results
The objective of this study is the visualisation of diffuse and focal lesion in the brain in Multiple Sclerosis on higher main magnetic fields. Images from 1.5 Tesla MR scanners will be compared with images acquired at 3 Tesla and images made on 3…
The primary objective of our proposal is to determine embryo development of donated human preimplantation embryos in four different culture media: (1) standard culture medium (control group), (2) culture medium with a uterine-like pH, (3) culture…
To investigate whether fecal microbial transplantation (FMT) from either allogenic (individuals with type 1 diabetes and a highly preserved beta cell fraction) or autologous (own) donor, administered every 8 weeks during 6 months through a small…
The primary objective of the study is to test the effectiveness of bumetanide across the whole spectrum of sensory processing disorders within ASD, ADHD and/or epilepsy. We also want to determine which subgroups (high/low IQ, comorbidities or not)…
Evaluating the effects of cognitive behavioral therapy for chronic insomnia (CBT-I) on sleep, general psychopathology, impulsivity and aggression in forensic psychiatric patients.
The objective of this proposal is to test in a proof-of-concept manner, whether the dietary fiber product WholeFiberTM yields an optimal gut and circulating SCFA concentration to reverse insulin resistance.
The aims of this study are to1) To identify information processing deficits that can help explain predict communication impairments, language deficits, social problems and increased risk for psychopathology.2) To assess if lack of regulation of…
Primary Objective: 1) To assess the short- and long-term prevalence of AMR genes in the microbiome of the gut in infants exposed to broad-spectrum antibiotics in the first week of life compared to controls. 2) To investigate the short- and long-term…
The aim of this study is to investigate the effect of a dietary intervention geared towards improved adherence to the Dutch dietary guidelines on the 10-year risk for recurrent vascular events (SMART risk score) in patients with cardiovascular…
The primary objective of this study is to examine clinical and radiographical parameters when executing:- adjuvant antibiotic therapy versus no antibiotic therapy in the resective surgical treatment of 0-, 1- and 2-wall bone defects due to peri-…
The primary objective of this study is to investigate the effects of personalized dietary guidance to increase the intake of fibre-rich foods, as recommended in the Dutch dietary guidelines, on cardiometabolic risk profile in individuals who have…
Primary objective:- To evaluate the safety and tolerability of colonisation with non-toxigenic C. difficile.- To establish the effective protocol to obtain colonisation with non-toxigenic C. difficile in the majority of subjects.Secondary objective…
To assess if prompt start of labour (<16 hours) of a fetus with RFM, based on CPR <1.1 in term pregnancy will improve the neonatal outcome (including perinatal mortality and long-term (neurodevelopmental) outcome) and maternal outcome…
To investigate the effect of preoperative protein supplementation on Hoffa*s fat pad, synovium, tendon, bone, muscle, ligament, menisci, and cartilage protein synthesis of the OA knee.
Primary Objectives: • To study the causal role of inflammation in affecting food-related effort-based decision making in brain and behaviour in overweight and obese participants by employing a placebo-controlled intervention design with the anti-…