31 results
The main research objectives for the proof-of-concept study are to show the feasibility and safety of a daily cycle of feeding and fasting in critically ill children of different age-groups, that will trigger an adequate fasting response while…
Is priming of the cervix, as part of induction of labour:* At home cost-effective and safe compared to the hospital?* with oral misoprostol cost-effective and safe compared to a Foley catheter?
The aim of this randomized controlled pilot study is to investigate the feasibility and to improve the functional recovery of a patient, by providing them with a multimodal prehabilitation program consisting of supervised physical exercise and/or…
Primary Objective:to assess the safety and tolerability of TAK-018 in postoperative subjects with CD afterlaparoscopic ileocecal resection with primary anastomosis.Secondary Objectives:to evaluate the impact of TAK-018 on intestinal inflammation…
Primary objective: To evaluate effectiveness, directly after intervention, of an individual face to face Managing Fatigue program on participation for people with NMD, including FSHD or MM compared to a control group receiving usual care.Secondary…
To quantify clinical and histological changes of the skin in promoting early wound healing when SVF + PRP injectable is used as treatment in comparison to SVF and PRP alone.
Objectives: To investigate the effect of a daily sachet of probiotics on vitamin K status for 12 weeks vs placebo.
Relevancy: Groin explorations are regularly performed procedures in vascular surgery. To date, the chosen technique will be either electrocoagulation or the Ligasure, depending on the operator*s preference. It is yet unclear whether the chosen…
The primary objective is to investigate the effect of 12 weeks of supplementation with 3.5g/day of rumenic acid on episodic memory in older men and women at risk of cognitive impairment. Secondary objectives include working memory, attention,…
The objective of this study is to analyse the hypothesis that intravenous milrinone used in conjunction with iNO results in the reduction in the time on iNO therapy and the time spent on invasive ventilation in infants * 34 weeks gestation and *…
In this study, we will investigate whether GAME musical training can provide additional benefits to CI users. The project is designed to provide scientific evidence for a music training program that will be aimed at to also be fun and engaging for…
Primary Objective: The primary objective of this randomized controlled study is to assess the safety and efficacy of the VITARIA* System when added to stable, guideline-directed medical therapy for patients with heart failure and reduced left…
Objectives:Primary objective:To evaluate the efficacy of the 3 selected dose regimens of Padsevonil (PSL) administered concomitantly with up to 3 antiepileptic drugs (AEDs) compared with Placebo for treatment of observable focal-onset seizures in…
The primary objective is twofold. First, we aim to investigate how the brain responds to acute stress and, second, which factors explain variability underlying brain activity following acute stress. The study population consists of extremely preterm…
Assess cognitive efficacy of gantenerumab, solanezumab in individuals who have mutations causing dominantly inherited Alzheimer's disease as measured by change in the DIAN-TU cognitive composite score between baseline and a minimum of 4 years.…
The primary goal is to investigate whether treatment on the MPU leads to a reduction of 'disruptive behavior' compared to CAU. Secondary goals are: to investigate whether treatment at the MPU influences the costs of care for patients,…
To investigate if patient controlled sublingual sufentanil tablets as compared to patient controlled intravenous morphine lead to improved independent mobilization on postoperative day 1 after laparoscopic donor nephrectomy (LDN).
Primary Objective* To evaluate the efficacy of VX-561Secondary Objectives* To evaluate the pharmacodynamic (PD) effect of VX-561* To evaluate the pharmacokinetics (PK) of VX-561, IVA, and relevant metabolites* To evaluate the safety and tolerability…
The primary objective of this study is to determine the effect of intervention with a CI in post lingual adult patients with progressive severe hearing loss and thus residual hearing, compared to standard care with hearing aids, on societal related…
The primary objective of this study is to compare the overall survival (OS) associated with rAd-IFN, when administered with celecoxib and gemcitabine, versus that associated with celecoxib and gemcitabine alone for the treatment of patients with MPM…