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The role of skin sodium accumulation in chronic kidney disease

Main objectivesCohort study:To investigate the prognostic implications of skin sodium accumulation for CKD patients.Sodium excretion intervention study:To study the effect of increased renal sodium excretion, with and without …

Stress system dynamics in childhood trauma-related depression

The primary objective is to investigate if the stress-induced dynamics across stress systems are impaired in patients with CT-related depression compared to non-CT-related depression and healthy controls. The secondary objective is to examine how…

A prospective, multi-centre, repeated measures, traditional feasibility study investigating neural health correlates with outcomes and evaluating focused multipolar implementation in the Phoenix Research System for newly implanted adult cochlear implant recipients.

This traditional feasibility study intends to inform a future pivotal trial in the following two ways. Firstly, it aims to evaluate the potential of neural health metrics triggered by FMS, to predict the implant recipient*s auditory performance -…

Optimal postoperative chest tube and pain management in patients surgically treated for primary spontaneous pneumothorax; a randomized controlled trial.

Our objective is to compare the efficacy of early chest tube removal combined with single-shot PVB versus standard treatment (chest tube for at least 3 days and thoracic epidural analgesia (TEA)) after surgery for PSP. Efficacy is defined as…

BradycArdia paCemaKer with AV interval modulation for Blood prEssure treAtmenT (BACKBEAT Trial)

The primary objective of the study is to determine whether AVIM therapy in combination with medical therapy is more effective at reducing ambulatory systolic blood pressure (aSBP) and to determine whether AVIM therapy is safe.