18 results
The overall objective of this study is to examine specific cardio-metabolic and cardiovascular parameters in women of subfertile couples. This study protocol is divided in 3 studies to evaluate several cardio-metabolic/cardiovascular parameters in…
Primary objectives:To establish the lowest effective dose using physiological and subjective measures of sexual arousal.To evaluate and compare the pharmacokinetics of testosterone and its metabolites following administration of three (3) doses (0.…
To test The Selection Failure hypothesis by assessing A) the degree of embryo invasiveness and decidual acceptance (the quality of decidualization, endometrium-embryo communication and endometrial stromal cell (ESC) migration) and B) the angiogeneic…
Primary objectives:To confirm the lack of effect of 0.5 mg sublingual testosterone on physiological and subjective measures of sexual arousal in women with HSDD. Secondary objective:To confirm the lack of effect of 0.5 mg sublingual testosterone on…
The present study is designed to validate the Dutch IIEF. The psychometric properties of the Dutch version of the IIEF will be investigated.
To investigate the effect of various dose regimens of Cyclogest® on secretory transformation of the endometrium in comparison to Crinone® and placeboTo investigate single and multiple dose pharmacokinetics of Cyclogest®To investigate safety and…
To assess whether close rectal restorative proctocolectomy with IPAA has a better outcome regarding postoperative vaginal vasocongestion and reported psychological and sexual functioning then IPAA by TME restorative proctocolectomy.
Comparing fertilty of male galactosemia patients to a control group
The objective of this observational study is the safe introduction of clinical applied IVM in The Netherlands. During this study, the number and quality of the oocytes and embryos will be studied as well as pregnancy development. Emphasis will be on…
In this study we aim to compare the effect of two different ovarian stimulation protocols on embryo quality in a group of women of 39 years or younger, in a prospectively randomized controlled trial. PGS will be performed to assess chromosomal…
Objectives1. To assess the prevalence of sexual dysfunction in a Dutch cohort of female childhood cancer survivors.2. To assess the disease-associated risk factors for sexual dysfunction (type of treatment, age at treatment) in female childhood…
We will assess the correlation between the incidence of early pregnancy loss and the successrate of ART in women with unexplained infertility. We will also investigate the difference in the incidence of early pregnancy loss in women with unexplained…
The purpose of this study is to investigate whether the hyperactive pelvic floor syndrome can be assessed by objective measurement. This will be done by means of a newly developed instrument, the so-called VPA/EMG/sensibility-combiprobe, that…
The objective of this study is to investigate the intra-individual change in AMH levels over several years in female RA patients.
This DCOG-LATER project proposal aims to characterize the overall, disease and treatment-related risks of sexual dysfunction and delays in psychosexual development in a Dutch cohort of 5-year CCS treated in the period 1960-2001 and to evaluate the…
To evaluate the long-term effects of GH-therapy on metabolic profile and risk factors for cardiovascular diseases in adults (aged 25-35 years) born SGA and compare this with non-treated adults born SGA and with adults born AGA.
To determine whether MTX can be quantified in seminal plasma and spermatozoa of MTX-naïve and chronic-MTX users, and to compare the concentration of MTX in seminal fluid and spermatozoa between MTX-naïve users and chronic-MTX users and to evaluate…
The goal of this study is to elucidate whether there is a difference in endometrial parameters (determining endometrial receptivity) between women with reproductive failure: RIF and RM. Secondly we will investigate how the endometrial parameters of…