15 results
Hypothesis: gaseous signaling molecules influence placental vasomotor activity to compensate for hypoxemia. Metabolites of these vasoactive molecules can be found in the blood and urine and can indicate whether this (compensatory) mechanism is used…
Primary Objective: To assess the hemodynamical effects of administration of AS in FGR fetuses and to compare these effects with those that occur in appropriate for gestational age (AGA) fetuses. Secondary Objective(s): To investigate the effect of…
Both RCTs and long-term follow-up studies are required to establish optimal fetal management and provide clinicians a better understanding of the impact of these early interventions on child development in order to improve the quality of antenatal…
The primary objective is to determine if there is an association between the presence of vertebral and/or rib anomalies and congenital malformations, aneuploidy or adverse fetal outcome, in order to assess whether detailed evaluation of the…
To establish benchmark values in healthy control fetuses, to compare these with our cohort of fetuses with severe CHD.
1. To evaluate the clinical usefulness of STIC with post-process rendering capability. Our goal is to investigate whether STIC gives more accurate information about a suspected cardiac anomaly, compared to conventional 2D ultracardiography.2. To…
An explanation of the complete spectrum of anomalies seen in fetuses with increased NT could be a disturbed endothelial differentiation related to the cardiovascular development. Cardiac defects form the severe end of the spectrum. More data, both…
The primary objective of this study will be to evaluate the cardiac adaptation due to hemodynamic changes in monochorionic twin pregnancies complicated by TTTS and sIUGR, by evaluating the size and the growth pattern of the pulmonary artery and the…
The goal of this study is to obtain insight into possible differences in macrophage and monocyte populations in uncomplicated pregnancies and pregnancies complicated by FGR.
Primary objective: To investigate baseline* left ventricle longitudinal strain rate values in a population of growth restricted fetuses and to compare these with a population of appropriate for gestational age fetuses.Secondary objective: To…
The aim of this study is to determine whether white blood cells from pregnant women are more susceptible to infection with the Zika virus compared to white blood cells from non-pregnant women. We do this by collecting two tubes of blood from…
Determine the number of hypoglycemic events (fasting and postprandial) during post-bariatric pregnancies compared to non-bariatric pregnancies (with obese and healthy BMI) using continuous glucose monitoring and its effects on fetal growth.
This proposal aims to evaluate the use of STE as a diagnostic tool for early diagnosis of impaired fetal growth in twins. The results from this proposal will be beneficial from a public health perspective, as it will lead to accurate and early…
To investigate the effect of increasing gestation on fetal myocardial deformation values.To explore fetal heart rate variability and fetal ECG waveform parameters in both healthy and growth-restricted fetuses, measured with non-invasive fetal…
This research aims to determine factors involved in subfertility and serious pregnancy complications that arise early in pregnancy. Due to increased insight into the pathogenesis of these conditions, primary prevention should ultimately be possible.