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Improving physical health and lifestyle behaviors in patients with serious mental illness: a cluster randomized controlled trial on the effectiveness of the nurse-led GILL eHealth intervention

Primary objective (after 1 year)- To evaluate the effectiveness of the nurse-led GILL eHealth intervention in patients with serious mental illnessSecundary objectives (after 1 year)- Improve metabolic syndrome severity- Improve fitness, physical…

COBRA re-KAI study: research into the immune response of COVID-19 revaccination after stem cell transplant or B-cel depleting immuno(chemo)therapy.

To answer the following questions: 1. Who are the patients that need to be revaccinated?2. How many vaccinations are needed to restore SARS-CoV-2 immunity?3. Can the number of vaccinations needed to restore SARS-CoV-2 immunity be predicted?To…

Increasing impact through technology: A randomized controlled trial to determine the effectiveness and cost-effectiveness of an innovative, data-supported, personalized treatment for anxiety and mood disorders.

The primary aim of the proposed study is to evaluate the effectiveness (1) and cost-effectiveness (2) of a DST for patients with anxiety and/or mood disorders in comparison to UC.The secondary aims are: 3) to identify what works for whom by…

The effect of algae oil supplements on functional immune response and bioavailability of lipids in blood, a pilot study

The primary objective is to estimate functional immune response in isolated peripheral blood mononuclear cells (PBMCs; ratio of pro-inflammatory; i.e. PGE2, IL-1β, IL-6, IL-8, IFN*, TNFα, CCL2 and CCL5, and anti-inflammatory markers; i.e., IL-4 and…