10 results
To study the effect of fructo-oligosaccharides on functional constipation.
To assess the effect of amitriptyline on gastro-esophageal symptom severity and on esophageal sensitivity to acid perfusion and balloon distension in patients with documented functional heartburn.
To obtain more information about the effects of capsaicin and cinnamaldehyde on the intestine, these substances will be infused directly in the duodenum. Hereafter, the permeability of the intestine, gallbladder motility and the effects on satiety…
The study aims to investigate the effects of moderate ethanol drinking on the intestinal permeability and the tight junction complex. If there increase in the intestinal permeability, these effects will be investigated at molecular level.
We would like to modulate the serotonin system with acute tryptophan depletion (ATD) and 5-hydroxytryptophan (5-HTP). ATD is based on ingestion of an amino acid drink devoid of the precursor of serotonin and hence caused a decreased serotonin level…
To study the safety and digestive tolerance of recombinant human Lactoferrin (rhLF) as expressed in milk of transgenic cattle.
Investigate the effect of administration of CBD by means of CanChew® chewing gum versus a placebo on pain, IBS symptoms and perceived wellbeing in patients with IBS.
To assess the effect of Iberogast on heartburn, the incidence of reflux episodes and oesophageal sensitivity in patients with functional dyspepsia.
The primary objective of this study is to determine the effect of short-term Turmipure GOLD® supplementation on LPS translocation in IBS-D and IBS-M patients after a high-fat challenge.The secondary objective of this study is to determine the effect…
To assess the effect of Ziverel on esophageal sensitivity to acid, mucosal barrier function and reflux symptoms in patients with PPI-refractory reflux symptoms.