18 results
To asses the effect of Prucalopride on esophageal contraction characteristics and lower esophageal sphincter pressure, gastric emptying and esophageal reflux parameters in healthy male subjects
Primary Objective: To determine oral, gastric and duodenal lipid degradation of fat preloads .Secondary Objectives: To study how the oro-gastro-intestinal digestion of these fat preloads relates to: - Colloidal stability. For this we will monitor…
Primary: • Assess effect of AN-PEP on gluten epitope degradation in the duodenumSecondary: • Assess effect of AN-PEP on gluten epitope degradation in the stomach• Assess effect of meal caloric content on the efficacy of AN-PEP on gluten epitope…
Primary:to examine the effect of co-administration with omeprazole on the pharmacokinetics of SSP-002358.Secondary:to provide additional safety information for SSP-002358 when administered alone or in combination with omeprazole.
The aim of this study is to gain insight in the mechanisms that may be involved in the effects of plant sterol drinks on gastric emptying and gallbladder motility. In order to test this, we compare the different effects of the consumption of a plant…
The primary objective of this study is to compare the stent migration rate of two metal expandable stents in patients with benign esophageal conditions.The secondary objectives are:• To compare the technical outcome.• To compare the functional…
The primary objective of this study is to establish the clinically relevance of extra protein supplementation on the height growth at children with Cystic Fibrosis. The secondary objectives of this study are to measure the effects of protein…
Objective: To compare the yield of Symptom Association Probability with two approaches to investigate patients with PPI-resistant symptoms: 24-hour pH monitoring off PPI and 24-hour impedance monitoring on PPI.
The aim of the study is to compare the effect jejunal with that of gastric tube feeding on abdominal symptoms.
To investigate the relationship between acute psychological stress and perception of acid in the distal oesophagus in healthy volunteers and GORD patients.
to investigate the relationship between acute psychological stress and perception of acid in the distal oesophagus in healthy volunteers and GORD patients.
The aims of this study are to assess the additional value of NBI in comparison to white-light endoscopy (WLE) for the detection and classification of HPs, SAs, MPs and adenomas in patients with HPS.
Determine the gastric and neural correlates of bloating.
To investigate the metabolism of curcumin in healthy volunteers and the effects of piprine and a lipid liquid formulation.
The primary objectives of this study are:1) To investigate the feasibility of the GISMO GEN1 System to monitor biomarkers in the gastrointestinal tract by studying the ingestible transit time, data coverage, participant experience, and serious…
The goal of this study is to investigate the most optimal way of canola protein processing on blood plasma amino acid responses in young females.
To evaluate the utility of the WATS system, as a potential substitute for the random sampling method that is currently recommended as an adjunct to targeted biopsy
Primary Objective: To determine effects of less exercise,30 min 70% Wmax, on intestinal function and immune response in blood, urine and saliva.Secondary Objective: Interlaboratory evaluation of the ergometertest performed in Groningen and Utrecht…