31 results
Total parathyroidectomy (PTX) in patients with secondary hyperparathyroidism (HPT2) is a more effective treatment than the use of Calcimimetica.
Primary hypotheses The primary hypothesis of the present study is that included patients who receive continuous or intermittent oxygen and bilevel positive pressure ventilation during fixed work rate treadmill exercise tests have shorter recovery…
Bezafibrate will significantly reduce post-prandial non-HDL cholesterol in patients with Familial Dysbetalipoproteinemia compared to placebo.
1. Methylphenidate (MPH) increases activation in task relevant areas and task performance 2. Hydrocortisone (HC) increases activation in task relevant areas and task performance 3. MPH + HC increase activation in task relevant areas, but might…
Increasing age is associated with a decrease in step length, gait speed, and mobility. Gait speed predicts numerous clinical conditions, including independence and mortality. A variety of exercise interventions are highly effective in maintaining…
Oral sodium butyrate use in subjects with type 1 diabetes will lead to an altered innate immune system response, ultimately improving beta cell function and glucose regulation.
In the process of developing a serious game for testing patients’ level of myocontrol a part of the test needs to be validated. In a previous trial we found differences between several tests that need further inspection. The current study focusses…
The aim of the current project is to investigate whether positive, strengths- and exception-focused CBT may be a useful supplement or an alternative to the traditional, problem-focused CBT approach for clinically depressed individuals. Primary…
Inhalation of once daily double dose of inhaled tobramycin targeted to the small airways by the Akita (1x 300 mg instead of 2x 150 mg) is more effective in reducing small airways obstruction compared with standard of treatment: twice daily…
Use of this walk-bike in daily life extends the range and everyday mobility of IPF patients, thereby decreases the level of dependency and social isolation, factors that are associated with quality of life. If, with this low-cost intervention, daily…
The main objective of the FitSupport study is to include 3000 supporters of the soccer clubs into the intervention through two different inclusion strategies; one digital and one personal recruitment strategy. These participants will be divided in…
Different studies have shown that a hunter-gatherer type diet is effective in improving glucose regulation and lipid profile. I want to investigate if the hypothese that this type of diet also reduces the number of physical and psychological…
(1) SNP will reduce the occurrence of psychomimetic side effects during exposure to low]dose ketamine; (2) SNP will reduce the ketamine]induced increase in blood pressure and cardiac output; (3) SNP is without effect on ketamine]induced pain…
Hypothesis: arterial oxygen concentrations induce dose-dependent hemodynamic and microcirculatory changes during oxygen supply in mechanically ventilated, post cardiac surgery, ICU patients. Aim: In this study we want to investigate the effects of…
To explore the effect of switching treatment from innovator infliximab (Remicade®) to infliximab biosimilar (Inflectra®, Remsima®) on efficacy, safety and immunogenicity in patients with rheumatoid arthritis (RA), spondyloarthritis (SpA) or…
We have developed a cueing application (app) for the Google Glass platform that can guide gait in PD-patients. Our initial observations showed that external cueing with the Google Glass application decreased the number and duration of FOG episodes…
One-stage breast reconstruction with contralateral mammaplasty using a breast sharing procedure is an oncologically safe concept.
To investigate whether amino acid area under the curve (AUC) and Cmax of product B is equivalent to amino acid AUC and Cmax of product A